Side Effects

   

Side Effects During/After Treatment

Cyberknife Radiosurgery

Mild to moderate urinary problems and mild fatigue for 1-2 months; about 1% of patients need catheterization for urinary retention; resume normal activity immediately after treatment

External Beam Radiotherapy (EBRT)

Intensity-Modulated Radiotherapy (IMRT)

Mild urinary and bowel problems and mild fatigue for 2 months; need for catheterization for urinary retention is rare; resume normal activity immediately after treatment

Calypso-Guided EEBRT/IMRT

Mild urinary and bowel problems and mild fatigue for 2 months; need for catheterization for urinary retention is rare; resume normal activity immediately after treatment

High-Dose-Rate (HDR) Brachytherapy

Mild pain from catheters; moderate urinary problems and fatigue for 1-2 months; about 3% of patients need catheterization for urinary retention; resume normal activity 1-2 days after leaving the hospital
 

Low-Dose-Rate (LDR) Brachytherapy (Seed Implant)

Pain at needle insertions; mild to severe urinary symptoms for 1-3 months; brief, mild fatigue; about 8% of patients need catheterization of urinary retention; resume normal activity day after implant

 


   

Long-term Side Effects

Cyberknife Radiosurgery

Despite receiving a dose similar to brachytherapy, long-term urinary effects are not common and rectal injury is rare; 20-30% patients develop erectile dysfunction
One-millimeter accuracy protects surrounding tissues

External Beam Radiotherapy (EBRT)

Intensity-Modulated Radiotherapy (IMRT)

Long-term urinary and rectal injury is not common; approximately 1/3 of patients develop erectile dysfunction

Calypso-Guided EEBRT/IMRT

Long-term urinary and rectal injury is not common; approximately 1/3 of patients develop erectile dysfunction


High-Dose-Rate (HDR) Brachytherapy

Occasional long-term urinary effects; rectal injury is rare; approximately 1/3 of patients develop erectile dysfunction

 

Low-Dose-Rate (LDR) Brachytherapy (Seed Implant)

Frequent long-term urinary effects; rectal injury is not common; approximately 1/3 of patients develop erectile dysfunction