Photo of Oren K. Fix

Oren K. Fix, M.D., MSc


Professional Statement

Dr. Fix believes in a multidisciplinary, team-based approach to the care of patients with liver disease. He believes that medicine should be a partnership that involves patients in their health care decisions. Dr. Fix focuses on educating patients about their liver disease and spends time ensuring they leave his office with a better understanding of their disease and hopefully with some sense of control over their health. In his free time, Dr. Fix enjoys snowboarding in the winter and hiking and camping in the summer.

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University at Buffalo State University of New York School of Medicine & Biomedical Sciences
medical school, 1999
Boston University Medical Center
residency, Internal Medicine, 2002
Boston University Medical Center
fellowship, Gastroenterology, 2005
University of California San Francisco
fellowship, Transplant Hepatology, 2006

Board Certifications

American Board of Internal Medicine
American Board of Internal Medicine
Internal Medicine
American Board of Internal Medicine
Transplant Hepatology

Clinical Interests

  • Autoimmune Hepatitis
  • Cirrhosis
  • End Stage Liver Disease
  • Fatty Liver
  • Hemochromatosis
  • Hepatitis B
  • Hepatitis C
  • Liver Biopsy
  • Liver Disease
  • Liver Transplant
  • Malignant Neoplasm Of Liver
  • Metabolic Liver Disease
  • Organ Transplantation
  • Primary Biliary Cirrhosis
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  1. Fix OK, Soto JA, Andrews CW, Farraye FA. Gastroduodenal Crohn's disease. Gastroint Endosc 2004;60(6):985.
  2. Nunes D, Fleming C, Offner G, O'Brien M, Tumilty S, Fix O, Heeren T, Koziel M, Graham C, Craven DE, Stuver S, Horsburgh CR. HIV infection does not affect the performance of noninvasive markers of fibrosis for the diagnosis of hepatitis C virus-related liver disease. J Acquir Immune Defic Syndr 2005;40(5):538-44.
  3. Fix OK, Peters MG, Davern TJ. Eosinophilic hepatitis due to lamotrigine. Clin Gastroenterol Hepatol 2006;4(4):xxvi.
  4. Fix OK, Simon JT, Farraye FA, Oviedo JA, Pratt DS, Chen WT, Cave DR. Obscure gastrointestinal hemorrhage from mesenteric varices diagnosed by video capsule endoscopy. Dig Dis Sci 2006;51(7):1169-74.
  5. Fix OK, Damon LE, Bass NM. Amyloidosis localized to the liver. Clin Gastroenterol Hepatol 2007;5(2):e7.
  6. Fix OK. Selection criteria for liver transplantation in hepatocellular carcinoma: Can we ignore tumor stage? Evidence-Based Gastroenterology 2007;8(1):23-4.
  7. Fix OK, Locarnini SA, Peters MG. Virology and clinical management of HIV and hepatitis B coinfection. The PRN Notebook 2007;11(4):16-23.
  8. Fix OK, Bass NM, De Marco T, Merriman RB. Long-term follow-up of portopulmonary hypertension: effect of treatment with epoprostenol. Liver Transpl 2007;13(6):875-85.
  9. Fix OK. Does a latte a day keep the hepatologist away? Hepatology 2008;47(1):348-51.
  10. Chan EY, Larson AM, Fix OK, Yeh MM, Levy AE, Bakthavatsalam R, Halldorson JB, Reyes JD, Perkins JD. Identifying risk for recurrent hepatocellular carcinoma after liver transplantation: implications for surveillance studies and new adjuvant therapies. Liver Transpl 2008;14(7):956-65.
  11. Fix OK and Kowdley KV. Hereditary hemochromatosis. Minerva Med 2008;99(6):605-17.
  12. Halldorson JB, Bakthavatsalam R, Fix O, Reyes JD, Perkins JD. D-MELD, a simple predictor of post liver transplant mortality for optimization of donor/recipient matching. Am J Transplant 2009;9(2):318-26.
  13. Perkins JD, Halldorson JB, Bakthvatsalam R, Fix OK, Carithers RL, Reyes JD. Should liver transplantation in patients with model for end-stage liver disease scores <or= 14 be avoided? A decision analysis approach. Liver Transpl 2009;15(2):242-54.
  14. Lai EJ, Calderwood AH, Doros G, Fix OK, Jacobson BC. The Boston Bowel Preparation Scale: A valid and reliable instrument for colonoscopy-oriented research. Gastrointest Endosc 2009;69(3 Pt 2):620-5.
  15. Nunes D, Fleming C, Offner G, Craven D, Fix O, Heeren T, Koziel MJ, Graham C, Tumilty S, Skolnik P, Stuver S, Horsburgh CR, Cotton D. Noninvasive markers of liver fibrosis are highly predictive of liver-related death in a cohort of HCV-infected individuals with and without HIV infection. Am J Gastroenterol 2010;105(6):1346-53.
  16. Vagefi PA, Klein I, Gelb B, Hameed B, Moff SL, Simko JP, Fix OK, Eilers H, Feiner JR, Ascher NL, Freise CE, Bass NM. Emergent orthotopic liver transplantation for hemorrhage from a giant cavernous hepatic hemangioma: case report and review. J Gastrointest Surg 2010;15(1):209-14.
  17. Calderwood AH, Lai EJ, Fix OK, Jacobson BC. An endoscopist-blinded, randomized, controlled trial of a simple visual aid to improve bowel preparation for screening colonoscopy. Gastrointest Endosc 2011;73(2):307-14.
  18. Mukhtar NA, Fix OK. Portopulmonary hypertension. J Clin Gastroenterol 2011;45(8):703-10.
  19. Findlay JY, Fix OK, Paugam-Burtz C, Lui L, Sood P, Tomlanovich SJ, Emond J. Critical care of the end stage liver disease patient awaiting liver transplantation. Liver Transpl 2011;17(5):496-510.
  20. Raval Z, Harinstein ME, Skaro AI, Erdogan A, DeWolf AM, Shah SJ, Fix OK, Kay N, Abeccassis MI, Gheorghiade M, Flaherty JD. Cardiovascular risk assessment of the liver transplant candidate. J Am Coll Cardiol 2011;58(3):223-31.
  21. Cascino MD, McNabb B, Gardner DG, Woeber KA, Fox AN, Wang B, Fix OK. Acute liver failure with thyrotoxicosis treated with liver transplantation. Endocr Pract 2013;19(3):e57-60.
  22. Fix OK. Acute Liver Failure: Peritransplant Management and Outcomes. Clinical Liver Disease 2013;2(4):165-8.
  23. Karvellas CJ, Fix OK, Battenhouse H, Durkalski V, Sanders C, Lee WM. Outcomes and complications of intracranial pressure monitoring in acute liver failure: a retrospective cohort study. Crit Care Med 2014;42:1157-67.
  24. Regalia K, Zheng P, Sillau S, Aggarwal A, Bellevue O, Fix OK, Prinz J, Dunn S, Biggins SW. Demographic factors affect willingness to register as an organ donor more than a personal relationship with a transplant candidate. Dig Dis Sci 2014;59:1386-91.
  25. Rose S, Fix OK, Shah BJ, Jones TN, Szyjkowski RD. Entrustable professional activities for gastroenterology fellowship training. Published simultaneously in: Gastroenterol 2014;147:233-42, Gastrointest Endosc 2014;80:16-27, Neurogastroenterol Motil 2014;26:1204-14, and Hepatology 2014;60:433-43.
  26. Long D, Fix OK, Deng X, Seielstad M, Lauring AS, and the Acute Liver Failure Study Group. Whole genome sequencing to identify host genetic risk factors for severe outcomes of hepatitis A virus infection. J Med Virol 2014;86:1661-8.
  27. Fontana RJ, Ellerbe C, Durkalski VE, Rangnekar A, Reddy RK, Stravitz T, McGuire B, Davern T, Reuben A, Liou I, Fix O, Ganger DR, Chung RT, Schilsky M, Han S, Hynan LS, Sanders C, Lee WM, and the US Acute Liver Failure Study Group. Two-year outcomes in initial survivors with acute liver failure: results from a prospective, multicentre study. Liver Int 2015;35:370-80.
  28. Jen KY, Fix OK, Foster EN, Laszik ZG, Ferrell LD. Monoclonal light chain deposits within the stomach manifesting as immunotactoid gastropathy. Ultrastruct Pathol 2015;39:62-8.
  29. Rich NE, Sanders C, Hughes RS, Fontana RJ, Stravitz RT, Fix O, Han SH, Naugler WE, Zaman A, Lee WM. Malignant infiltration of the liver presenting as acute liver failure. Clin Gastroenterol Hepatol 2015 May;13:1025-8.
  30. Yao FY, Mehta N, Flemming J, Dodge J, Hameed B, Fix O, Hirose R, Fidelman N, Kerlan RK Jr, Roberts JP. Downstaging of hepatocellular cancer before liver transplant: Long-term outcome compared to tumors within Milan criteria. Hepatology 2015;61:1968-77.
  31. Kwong AJ, Fix OK. Update on the management of the liver transplant patient. Curr Opin Gastroenterol 2015;31:224-32.
  32. Karvellas CJ, Tillman H, Leung AA, Lee WM, Schilsky ML, Hameed B, Stravitz RT, McGuire BM, Fix OK. Acute liver injury and acute liver failure from mushroom poisoning in North America. Liver Int 2016;36:1043-50.
  33. Fix  OK, Stock PG, Lee BK, Benson MD. Liver transplant alone without kidney transplant for fibrinogen Aα-chain (AFib) renal amyloidosis. Amyloid 2016;23:132-3.
  34. Reuben A, Tillman H, Fontana RJ, Davern T, McGuire B, Stravitz RT, Durkalski V, Larson AM, Liou I, Fix O, Schilsky M, McCashland T, Hay JE, Murray N, Shaikh OS, Blei A, Ganger D, Zaman A, Han SHB, Chung RT, Smith A, Brown RS Jr, Crippin J, Harrison E, Koch D, Munoz S, Reddy R, Rossaro L, Satyanarayana R, Hassanein T, Hanje J, Olson J, Subramanian R, Karvellas C, Hameed B, Doo E, Sherker AH, Robuck P, Lee WM. Improved outcomes in adults with acute liver failure (ALF) from 1998 to 2013: An update from the US Acute Liver Failure Study Group. Ann Intern Med 2016;164:724-32.
  35. Fix OK, Liou I, Karvellas CJ, Ganger DR, Forde KA, Subramanian RM, Boylan A, Hanje J, Stravitz RT, Lee WM. Development and pilot of a checklist for management of acute liver failure in the intensive care unit. PLoS ONE 2016;11(5):e0155500.
  36. Roberts DW, Lee WM, Hinson JA, Bai S, Swearingen CJ, Stravitz RT, Reuben A, Letzig L, Simpson PM, Rule J, Fontana RJ, Ganger D, Reddy KR, Liou I, Fix O, James LP. An immunoassay to rapidly measure acetaminophen protein adducts accurately identifies patients with acute liver injury and failure. Clin Gastroenterol Hepatol 2017;15:555-62.
  37. Russo MW, Koteish A, Fuchs M, Reddy G, Fix O. Workforce in Hepatology: Update and a critical need for more information. Hepatology 2017;65:336-40.
  38. Girard JM, Decker K, Lai J, Logan A, Gill R, Fix OK. Acute liver failure secondary to hemophagocytic lymphohistiocytosis during pregnancy: a diagnostic dilemma and deadly disease. ACG Case Rep J 2016;3:e162.
  39. Koch DG, Speiser JL, Durkalski V, Fontana RJ, Davern T, McGuire B, Stravitz RT, Larson AM, Liou I, Fix O, Schilsky ML, McCashland T, Hay JE, Murray N, Shaikh OS, Ganger D, Zaman A, Han SB, Chung RT, Brown RS, Munoz S, Reddy KR, Rossaro L, Satyanarayana R, Hanje AJ, Olson J, Subramanian RM, Karvellas C, Hameed B, Sherker AH, Lee WM, Reuben A. The natural history of severe acute liver injury. Am J Gastroenterol 2017. [Epub ahead of print]
  40. Fix OK, Spinelli T, Kowdley KV. Developing clinical research in a clinical hepatology practice. Clinical Liver Disease 2017;9:147-9.
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Professional Associations

American Association for the Study of Liver Diseases, American College of Physicians, American Gastroenterological Association, American College of Gastroenterology, Accreditation Council for Graduate Medical Education, American Association for Physician Leadership, American Medical InformaticsĀ Association
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  • English

Practice Locations

Oren K. Fix practices at one location

Swedish Organ Transplant and Liver Center
1124 Columbia Street
Suite 600
Seattle, WA 98104
Affiliated Facilities
  • Swedish Cherry Hill
  • Swedish First Hill
Medical Groups
Swedish Medical Group logo