Photo of John L. Mignone

John L. Mignone, M.D., Ph.D.

Robert M. and Patricia Arnold Endowed Medical Director for Heart Failure

Cardiology, Heart Failure and Transplantation Cardiology

Accepting New Patients


Professional Statement

In our clinic, you will receive the comprehensive care that a patient with heart failure requires. We have created a comprehnesive approach to managing heart failure allowing a patient a level of support unique to managing this disease. We aim to be your partner as we work together to make a treatment plan that best suits your needs and objectives.

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Accepts 43 Insurance Plans

Please contact the practice directly to confirm your health plan is accepted
  • Aetna Medicare Advantage HMO
  • Aetna Medicare Advantage PPO
  • Aetna PPO
  • Amerigroup Amerivantage Dual Coordination
  • Amerigroup Amerivantage HMO
  • Amerigroup Medicaid (Apple Health/Healthy Options/CHIP)
  • Beacon Health Options PPO (Behavioral Health)
  • CHPW Medicaid (Apple Health/Healthy Options/CHIP)
  • CHPW Medicare Advantage
  • Cigna Behavioral Health
  • Cigna PPO
  • Coordinated Care Ambetter HMO
  • Coordinated Care Medicaid (Apple Health/Healthy Options/CHIP)
  • Coventry/First Health PPO
  • First Choice PPO
  • HealthSmart (Interplan) PPO
  • Humana Medicare Advantage
  • Humana PPO
  • Kaiser (Contract Limitations)
  • Medicaid of Washington
  • Medicare
  • Molina Exchange HMO
  • Molina Medicaid (Apple Health/Healthy Options/CHIP)
  • Molina Medicare Advantage
  • Multiplan PPO
  • Optum
  • PacMed USFHP
  • Premera Heritage
  • Premera Heritage Signature
  • Premera Medicare Advantage HMO
  • Providence Health Plan Medicare Advantage
  • Regence MedAdvantage PPO
  • Regence PPO
  • Triwest VAPC3/Choice Card
  • United Behavioral Health Medicaid
  • United Behavioral Health Medicare Advantage
  • United Behavioral Health PPO
  • United HealthCare HMO
  • United HealthCare Medicaid (Apple Health/Healthy Options/CHIP)
  • United HealthCare Medicare Advantage
  • United HealthCare PPO
  • Workers' Compensation (L&I)
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Duke University
medical school, 2006
University of Washington
residency, Internal Medicine, 2008
University of Washington
fellowship, Advanced Heart Failure and Transplant Cardiology, 2014

Board Certifications

American Board of Internal Medicine
Advanced Heart Failure and Transplant Cardiology
American Board of Internal Medicine
Cardiovascular Disease
American Board of Internal Medicine
Internal Medicine

Clinical Interests

  • Advanced Heart Failure
  • Cardiac Amyloid
  • Cardiac Arrest
  • Cardiac Catheterization
  • Cardiac Disease In Pregnancy
  • Cardiac Sarcoidosis
  • Cardiomyopathy
  • Centrimag Ventricular Assist Device
  • Congestive Heart Failure
  • Extracorporeal Membrane Oxygenation
  • Heart Transplant
  • Hypertrophic Cardiomyopathy
  • Infiltrative Disorders Of The Heart
  • Intra-Aortic Balloon Pump
  • Mechanical Circulatory Support
  • Myocarditis
  • Sudden Cardiac Death
  • Transplantation Medicine
  • Ventricular Assist Device Bridge-To-Recovery
  • Ventricular Assist Device Bridge-To-Transplant
  • Ventricular Assist Device For Destination Therapy
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Personal Interests

I am personally interested in genetic cardiomyopathies, cardiac amyloidosis and advanced heart failure management with ventricular assist devices. I have a strong interest in research, and currently, the heart failure clinic is enrolling in over 10 heart failure related clinical trials. We also have the longest practice knowledge in the Pacific Northwest using the cardiomem device for managing very complicated heart failure patients, particularly those people far from Seattle to help keep close management of the disease from the comfort of your own home.
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Professional Associations

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  • English

Practice Locations

John L. Mignone practices at two locations

Affiliated Facilities
  • Swedish Cherry Hill
  • Swedish First Hill
  • Swedish Issaquah
Medical Groups
Swedish Medical Group logo