High-Grade Gliomas

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Ben and Catherine Ivy Center for Advanced Brain Tumor Treatment

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High-grade gliomas are primary brain-cancer tumors that grow very rapidly. They require an immediate and aggressive approach to treating brain cancer.

High-grade gliomas are named for the type of brain cell found in the tumor. For example, a brain tumor made up of cells called astrocytes is called an astrocytoma. Tumors with oligodendrocyte cells are called oligodendrogliomas.

The different types of high-grade gliomas have more than one name – which can be a little confusing. The term "anaplastic" refers to tumors containing rapidly dividing cancer cells.

The names and alternative names of high-grade gliomas include:

  • Anaplastic Astrocytoma (Grade 3 Astrocytoma)
  • Anaplastic Oligodendroglioma (Grade 3 Oligodendroglioma)
  • Anaplastic Oligoastrocytoma (Anaplastic Mixed Gliomas or Grade 3 Oligoastrocytoma)
  • Glioblastoma (Grade 4 Astrocytoma or GBM)

Glioblastoma is the most aggressive form of brain cancer, and a primary focus of the Ivy Brain Tumor Center.