Organ Care Research

Research Team750

The Organ Care Research Department, which is dedicated to the Swedish Organ Transplant and Liver Center, has an ambitious agenda to support research in kidney, liver, pancreas, infectious diseases and organ transplantation. Through this research, our patients may have access to alternative and novel therapies.

Swedish Organ Care Research Team

  • Research manager
  • Clinical research coordinators
  • Clinical research nurse
  • Research assistant
  • Ph.D. scientist
  • Senior laboratory technician
Our research program includes observational studies, patient registries, clinical trials as well as laboratory-based research.  A major focus of our research program is in the area of liver disease.  We have ongoing clinical trials in cholestatic liver disease, alcoholic hepatitis, autoimmune hepatitis, hepatorenal syndrome and nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH).  Our research in NASH includes both basic and translational research in addition to therapeutic clinical studies, for which we have been continuously funded by the NIDDK since 2002.

Kidney transplant research has focused on trials related to increasing kidney allograft survival and improving outcomes for patients.  Ongoing clinical trials are investigating new immunosuppression therapies and the prevention, management and treatment of opportunistic viral infections.  We also are involved with registry trials looking at long-term safety and survival of donor and recipients following kidney transplant. 

Clinical Trial Options for Patients

Autoimmune hepatitis: a chronic, autoimmune disease of the liver that occurs when the body’s immune system attacks the liver.

Hemochromatosis: a condition caused by the hyper-absorption of iron from the diet, leading to increased iron deposition in the liver and other organs.

Hepatorenal syndrome: a type of kidney failure in patients with cirrhosis.

Nonalcoholic steatohepatitis: NASH is a chronic progressive liver disease due to fatty liver in the absence of alcohol abuse.

Primary biliary cholangitis (PBC): an auto-immune disease of the liver. It results from a slow, progressive destruction of the small bile ducts of the liver, causing bile and other toxins to build up in the liver.

Primary sclerosing cholangitis (PSC): is a long-term progressive disease of the liver and gallbladder characterized by inflammation and scarring of the bile ducts which normally allow bile to drain from the gallbladder.

For more information, contact:

Manager: Jodie Davila, RN, BSN 
Phone: 206-215-4384

Director: Kris V. Kowdley, M.D. 
Phone: 206-386-3660

Research Laboratory

Clinical Researchers