DECAAF II - Efficacy of DE-MRI-Guided Fibrosis Ablation vs. Conventional Ablation of Atrial Fibrillation

Description: To examine the efficacy of targeting atrial fibrosis tissue during an ablation procedure treating persistent Atrial Fibrillation.

Eligibility:

Inclusion Criteria:

• Patients with persistent AF undergoing first AF ablation.
• Must have some proportion of atrial fibrosis.
• Able to understand and willing to sign the Informed Consent Form.
•  Age greater than or equal to 18 years.

Exclusion Criteria:

• Contraindication for DE-MRI with a full dose of Gadonlinium-based contrast agent.
• Previous left atrial ablation or surgical procedure.
• Women currently pregnant.
• Mental or physical inability to take part in the study.
• Uncontrolled hypertension.
• Inability to be placed in MRI due to body mass.