DECAAF II - Efficacy of DE-MRI-Guided Fibrosis Ablation vs. Conventional Ablation of Atrial Fibrillation

To examine the efficacy of targeting atrial fibrosis tissue during an ablation procedure treating persistent Atrial Fibrillation.
NCT02529319
Heart & Vascular - Electrophysiology, Heart & Vascular
Darryl S. Wells, MD
University of Utah
Jeremy Gillis

Inclusion Criteria:

  • Patients with persistent AF undergoing first AF ablation.
  • Must have some proportion of atrial fibrosis.
  • Able to understand and willing to sign the Informed Consent Form.
  •  Age greater than or equal to 18 years.

Exclusion Criteria:

  • Contraindication for DE-MRI with a full dose of Gadonlinium-based contrast agent.
  • Previous left atrial ablation or surgical procedure.
  • Women currently pregnant.
  • Mental or physical inability to take part in the study.
  • Uncontrolled hypertension.
  • Inability to be placed in MRI due to body mass.
Jeremy Gillis
206-215-6573