While smoking marijuana may have recently been legalized, one shouldn’t conclude that it is necessarily healthy.
For individuals who treat lung cancer patients in the states of Washington and Colorado, the recently passed legislations raise serious concerns. Ironically, this happened on the eve of the 50th anniversary of the first US Surgeon General Report by Dr. Luther Terry in January 1964, which concluded that lung cancer is causally related to cigarette smoking. This report had followed decades of warnings by so-called common sense alarmists who had identified this as a major public health issue but who lacked the data to fully support their claims.
It is estimated that, in the US, we saw just over 225,000 new cases of lung cancer in 2012, 80 to 90% of these occurring in active or former cigarette smokers. That year, close to 160,000 American men and women died of their lung cancer. In the state of Washington alone, about 4,200 new cases were diagnosed. These numbers are qui...
Everyone sweats – but what if you had a condition that caused uncontrollable sweating in your hands?
Palmar hyperhidrosis is a benign condition where individuals experience uncontrollable sweating of their hands, way beyond their physiological needs. Hand sweating in such a scenario is often described as being present 24/7, may be worsened in situations of stress but also occurs out of nowhere in times of total rest and serenity. From the constant dampness the hands are exposed to, ulcerations and other skin related changes may develop. Many patients with this condition adopt a line of work and a life style that minimizes public encounters and avoid hand contact such as having to shake hands.
It has been known since the 1920s that by dividing the sympathetic chain (nerve) high up inside the chest, a procedure called thoracic sympathectomy, we can make the hands stop sweating. To achieve this surgically was quite an undertaking back then. The surgical trauma was such that histori...
What stage is my cancer, doc?
This is often the first question we get asked when meeting with a patient newly diagnosed with lung cancer. In this blog, I would like to briefly review the notion of lung cancer staging and its implications.
Staging allows us to define the extent of a cancer and determine its best available treatment. It also allows us to statistically estimate the prognosis of the cancer. Finally, adequate staging allows us to group patients with cancers of similar extent across different institutions or even countries and evaluate the efficacy of the treatment strategies and compare with new ones.
Staging can be clinical or pathological. Clinical staging is based on the information we obtain from X-rays and scans as well as from procedures where samples (biopsies) of different tissues are obtained in an effort determine what structures may be involved with the cancer. Pathological staging is only available when the cancer has been removed by surgery: i.e. whe...
Dr. Eric Vallieres is the lead investigator for the following clinical trial currently available at the Swedish Cancer Institute:
A Double Blind, Randomized, Placebo Controlled Phase II Study to Assess the Efficacy of recPRAME +AS15 Antigen-Specific Cancer Immunotherapeutic as Adjuvant Therapy in Patients with Resected PRAME Positive, Non-Small Cell Lung Cancer
Induction chemotherapy in the treatment of surgical lung cancer.
The use of air-leak sealants in lung surgery.
The use of adjuvant antigen specific vaccine therapy in resected lung cancers.
Breath-test evaluation in screening for lung cancer.
Trimodality Therapy for Malignant Pleural Mesothelioma
G. Buduhan, S. Menon, R. Aye, B. Louie, V. Mehta, E. Valli�res
Society of Thoracic Surgeons, 45th Annual Meeting. San Francisco, CA.
Jan. 27, 2009
Preliminary experience with minimally invasive thymectomy
Youssef S, Blitz M, Valli�res E, Aye RW, Louie BE
"Minimally Invasive Thymectomy has been successfully adopted at Swedish Medical Center"
Washington Chapter of the American College of Surgeons. Lake Chelan, WA. June 14, 2009
PUBLICATIONS & PRESENTATIONS
Schild SE, Ramalingam SS, Valli�res E. Management of Stage III Non-Small Cell Lung Cancer In: UpToDate, Basow, D (Ed), UpToDate, Waltham, MA, 2011.
Park DR, Valli�res E. Pneumomediastinum and Mediastinitis, Chapter 76: in Textbook of Respiratory Medicine 5th edition by Mason RJ, Broaddus VC, Martin TR, King TE, Schraufnagel DE, Murray JF and Nadel JA (editors), Elsevier Saunders (USA), : 1836-1858, 2010
Park DR, Valli�res E. Tumors and Cysts of the Mediastinum, Chapter 76: in Textbook of Respiratory Medicine 5th edition by Mason RJ, Broaddus VC, Martin TR, King TE, Schraufnagel DE, Murray JF and Nadel JA (editors). Elsevier Saunders (USA), : 1814-1835, 2010
Valli�res E. Role of surgery in multimodality therapy for small cell lung cancer. In: UpToDate, Basow, D (Editor), UpToDate, Waltham, MA, 2009.
Schild, S, West, H, Valli�res E. Management of stage I and stage II non-small cell lung cancer. In: UpToDate, Basow, D (Editor), UpToDate, Waltham, MA, 2009.
Farivar AS, Cerfolio RJ, Valli�res E, Knight AW, Bryant A, Lingala V, Aye RW, Louie BE. Comparing robotic lung resection with thoracotomy and video-assisted thoracoscopic surgery cases entered into the society of thoracic surgeons database. Innovations (Phila). 2014 Jan-Feb;9(1):10-5.
Deen SA, Wilson JL, Wilshire CL, Valli�res E, Farivar AS, Aye RW, Ely RE, Louie BE. Comparing robotic lung resection with thoracotomy and video-assisted thoracoscopic surgery cases entered into the society of thoracic surgeons database. Ann Thorac Surg. 2014 Mar;97(3):1000-7.
Wilson JL, Louie BE, Farivar AS, Valli�res E, Aye RW. Fully covered self-expanding metal stents are effective for benign esophagogastric disruptions and strictures. J Gastrointest Surg. 2013 Dec;17(12):2045-50
Hunt BM, Horton MP, Valli�res E. Bronchogenic carcinoid tumours that are 18F-fluorodeoxyglucose avid on positron emission tomography. Eur J Cardiothorac Surg. 2014 Mar;45(3):527-30.
Valli�res E, Renaud C. Clinical and economical impact of multiplex respiratory virus assays. Diagn Microbiol Infect Dis. 2013 Jul;76(3):255-61
Valli�res E, Pintos J, Lavou� J, Parent M�, Rachet B, Siemiatycki J. Exposure to welding fumes increases lung cancer risk among light smokers but not among heavy smokers: evidence from two case-control studies in Montreal. Cancer Med. 2012 Aug;1(1):47-58.
Louie BE, Kapur S, Blitz M, Farivar AS, Valli�res E, Aye RW. Length and pressure of the reconstructed lower esophageal sphincter is determined by both crural closure and Nissen fundoplication. J Gastrointest Surg. 2013 Feb;17(2):236-43.
Valli�res E, Saint-Jean M, Rallu F. Comparison of three different methods for detection of Shiga toxin-producing Escherichia coli in a tertiary pediatric care center. J Clin Microbiol. 2013 Feb;51(2):481-6.
Wagner OJ, Louie BE, Valli�res E, Aye RW, Farivar AS. Near-infrared fluorescence imaging can help identify the contralateral phrenic nerve during robotic thymectomy. Ann Thorac Surg. 2012 Aug;94(2):622-5
Egan M, Louie BE, Farivar AS, Wagner O, Valli�res E. Laparoscopic repair of gastric herniation after extrapleural pneumonectomy for mesothelioma. Ann Thorac Surg. 2012 May;93(5):e127-9.
Hunt BM, Farivar AS, Valli�res E, Louie BE, Aye RW, Flores EE, Gorden JA. Thoracoscopic talc versus tunneled pleural catheters for palliation of malignant pleural effusions. Ann Thorac Surg. 2012 Oct;94(4):1053-7.
Louie BE, Farivar AS, Aye RW, Valli�res E. Early experience with robotic lung resection results in similar operative outcomes and morbidity when compared with matched video-assisted thoracoscopic surgery cases. Ann Thorac Surg. 2012 May;93(5):1598-604; discussion 1604-5
Farivar AS, Louie BE, Aye RW, Horton MP, Valli�res E. Extrapleural pneumonectomy for primary pleural mullerian tumor in a young woman. Ann Thorac Surg. 2012 Jan;93(1):
Valli�res E, Peters S, Van Houtte P, Dalal P, Lim E. Therapeutic advances in non-small cell lung cancer. Thorax. 2012 Dec;67(12):1097-101.
Valli�res E, Van Houtte P, Travis WD, Rami-Porta R, Goldstraw P; International Association for the Study of Lung Cancer (IASLC) International Staging Committee. Carcinoma in situ at the bronchial resection margin: a review. J Thorac Oncol. 2011 Oct;6(10):1617-23.
Louie BE, Kapur S, Farivar AS, Youssef SJ, Gorden J, Aye RW, Valli�res E. Safety and utility of mediastinoscopy in non-small cell lung cancer in a complex mediastinum. Ann Thorac Surg. 2011 Jul;92(1):278-82.
Youssef SJ, Louie BE, Farivar AS, Blitz M, Aye RW, Valli�res E. Comparison of Open and Minimally Invasive Thymectomies at a Single Institution, American Journal of Surgery. 199 (5): 589-93, 2010
Pisters KMW, Valli�res E, Bunn P, Crowley JC, Chansky K, Ginsberg RJ, Gandara D. "Surgery With or Without Preoperative Paclitaxel and Carboplatin in Early-Stage Non-Small Cell Lung Cancer: Southwest Oncology Group Trial S9900, an Intergroup, Randomized, Phase III Trial", Journal of Clinical Oncology 28: 1843-49, April 10 2010.
Page B, Blitz M, Louie B, Aye R and Valli�res E. "Pulmonary Resection of NSCLC can be performed safely following definitive chemoradiotherapy". (Abstract) Oral presentation 13th World Conference on Lung Cancer, San Francisco, CA August 1st 2009, Journal of Thoracic Oncology. 4(9) Supplement 1:S301. September 2009.
Valli�res E: “More Questions about Neoadjuvant Chemotherapy in Lung Cancer”, an invited commentary, Oncology 23(10): 892, 896, September 2009.
Valli�res E, Shepherd FA, Crowley JJ, Van Houtte P, Postmus PE, Carney D, Chansky K, Shaikh Z, Goldstraw P,on behalf of the International Association for the Study of Lung Cancer International Staging Committee*, and Participating Institutions. The IASLC Lung Cancer Staging Project: Proposals regarding the relevance of TNM in the Pathological Staging of Small Cell Lung Cancer in the Forthcoming (Seventh) Edition of theTNM Classification for Lung Cancer. Journal of Thoracic Oncology 4(9): 1049-59, September 2009.
Buduhan G, Menon S, Aye R, Louie B, Mehta V, Valli�res E. "Induction Chemotherapy, Extrapleural Pneumonectomy and Hemithoracic Radiation Therapy for Malignant Pleural Mesothelioma". Annals of Thoracic Surgery 88(3) :870-6, September 2009.
Hunt BM, Valli�res E, Buduhan G, Aye R, Louie B: "Sarcoidosis as a benign cause of lymphadenopathy in cancer patients". American Journal of Surgery, 197: 629-32, May 2009.
Travis WD, Brambilla E, Rami-Porta R, Valli�res E, Tsuboi M, Rusch V, Goldstraw P, on behalf of the International Staging Committee§ and Participating Institutions. "Visceral Pleural Invasion: Pathologic Criteria and Use of Elastic Stains: Proposal for the 7th Edition of the TNM Classification for Lung Cancer". Journal of Thoracic Oncology 3(12):1384-90, December 2008.
Rami-Porta R, Ball D, Crowley JJ, Giroux D, Jett J, Travis WD, Tsuboi M, Valli�res E, Goldstraw P, on behalf of the International Association for the Study of Lung Cancer. International Staging CommitteeIASLC Staging Project: T-descriptors: E05-02. Journal of Thoracic Oncology. 2(8) Suppl. 4:S227-S228, August 2007.
Presentations & Education:
Valli�res E. Faculty, 7th Annual Winter Lung Cancer Conference: “Practical Implications of the New Staging System” and “Surgical Staging of NSCLC”, Key Biscayne, FLA. March, 2010
Valli�res E. Faculty, “Optimizing patient outcome: the multidisciplinary approach. The Surgeon’s Perspective”, ECCO 15th/ESMO 34th Joint Multidisciplinary Congress, Satellite Sponsored Symposium, Berlin, Germany. September, 2009
Valli�res E. Co-Chair, Fifth Annual Multidisciplinary Interactive Thoracic Oncology Conference, Seattle, WA. September, 2009
Valli�res E. Co-chair and discussant, “Proffered Papers: Therapeutic Strategies in Malignant Mesothelioma”, 13th World Conference on Lung Cancer, San Francisco, CA. August, 2009
Valli�res E. Faculty, AATS/STS General Thoracic Surgery Symposium, “Current Early Stage Lung Cancer Trials”, Boston, MA. May, 2009
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