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Photo of Pamela J Paley

Pamela J. Paley, MD

Languages: English
  • Gynecological Oncology
Accepting New Patients
Professional Statement
I provide exceptional and comprehensive treatment to women stricken with gynecologic cancers with a compassionate and caring approach. I enjoy the long-term partnerships made with my patients, and consider myself privileged to be able to help women confronted with cancer.
Stritch School of Medicine, Loyola University Chicago
Medical School
Duke University
University of Minnesota
Personal Interests
I met my husband, Jon Paley, who is also a physician in the area, while in training at Duke University. We have two children, to whom we devote much of our time. We enjoy an active life and spend time boating, traveling and skiing in British Columbia.
Board Certifications
  • American Board of Obstetrics and Gynecology, Obstetrics and Gynecology
  • American Board of Obstetrics and Gynecology, Gynecologic Oncology
Clinical Interests
  • abdominal cerclage
  • abdominal chemotherapy
  • abdominal cramps
  • abnormal pap
  • abnormal uterine bleeding
  • abortion
  • abortion information
  • amenorrhea
  • anemia of pregnancy
  • annual gynecological examination
  • anovulation
  • anovulatory bleeding
  • asymptomatic bacturia
  • atrophic vaginitis
  • atypical glandular cells of undetermined significance
  • atypical squamous cells of undetermined significance pap smear
  • bacterial vaginosis
  • bartholin's cyst
  • bartholin's gland carcinoma
  • benign breast lump
  • bicornuate uterus
  • birth control
  • bladder prolapse
  • bladder training
  • breast examination
  • breast lump
  • cancer of the oviduct
  • cancer of the vagina
  • candidiasis of vagina
  • cervical biopsy
  • cervical cancer
  • cervical conization
  • cervical dysplasia
  • cervical intraepithelial neoplasia
  • cervical polyp
  • chlamydia-female only
  • choriocarcinoma
  • chorionic villus sampling
  • colposcopy
  • condylomata acuminata
  • cryosurgery of cervix
  • cystitis
  • cystocele
  • da vinci hysterectomy
  • delayed menarche
  • delayed puberty
  • dermoid cyst
  • detrusor instability
  • diabetes in pregnancy
  • diabetic and newly pregnant
  • dilation and curettage
  • dysgerminoma of ovary
  • dyspareunia
  • dysuria
  • ectopic pregnancy
  • endometrial ablation
  • endometrial biopsy
  • endometrial cancer
  • endometrial hyperplasia
  • endometrioma
  • endometriosis
  • endometritis
  • enterocele
  • essure contraceptive
  • fallopian tube cancer
  • fallopian tube disorders
  • familial ovarian cancer
  • female anorgasmia
  • female genital problems
  • fibroid removal
  • fibroids
  • follicular cyst of ovary
  • galactocele
  • genital herpes, female
  • gestational trophoblastic disease
  • gynecologic cancer care
  • hormone replacement therapy
  • hot flashes
  • human papilloma virus
  • hydatiform mole
  • hyperemesis
  • hysterectomy
  • hysteroscopy
  • imperforate hymen
  • implanon
  • incomplete abortion
  • incomplete emptying of bladder
  • incomplete uterovaginal prolapse
  • increased frequency of micturition
  • intrauterine device
  • irregular menstruation
  • labial adhesions
  • laceration of vagina
  • laparoscopic hysterectomy
  • laparoscopic lysis of peritoneal adhesions
  • laparoscopy
  • laparoscopy pelvic lymphadenectomy
  • leiomyoma
  • leiomyosarcoma of uterus
  • lichen sclerosis
  • malignant neoplasm of cervix
  • malignant neoplasm of mesovarium
  • mastodynia
  • menometrorrhagia
  • menopause
  • menorrhagia
  • missed abortion
  • missed periods
  • nexplanon
  • oligomenorrhea
  • operations on cul-de-sac
  • oral contraceptive counseling
  • ovarian cyst
  • ovarian debulking surgery
  • ovarian failure
  • ovarian mass
  • ovarian torsion
  • overflow incontinence of urine
  • paget's disease of vulva
  • painful periods
  • pap smear
  • paratubal cyst
  • partial hysterectomy
  • pelvic abscess
  • pelvic adhesions
  • pelvic floor dysfunction
  • pelvic floor exercise
  • pelvic inflammatory disease
  • pelvic lymphadenectomy
  • pelvic malignancy during pregnancy
  • pelvic mass
  • pelvic organ prolapse
  • pelvic pain
  • pelvic varicose veins
  • perimenopause
  • perinatal mental health
  • permanent sterilization
  • pessary
  • placental disorders
  • polycystic ovary syndrome
  • post partum check-up
  • post partum mastitis
  • postcoital bleeding
  • postmenopausal bleeding
  • preconception counseling
  • preeclampsia
  • pregnancy
  • pregnancy counseling
  • premature adrenarche
  • premature ovarian failure
  • premenstrual syndrome
  • prenatal care
  • prenatal testing
  • preterm premature rupture of membranes
  • primary amenorrhea
  • prophylactic oophorectomy
  • radical trachelectomy
  • radical vulvectomy
  • recurrent urinary tract infection
  • robotic gynecological surgery
  • robotic myomectomy
  • robotic urological surgery
  • routine gynecological care
  • salpingo-oophoritis
  • sarcoma
  • selective estrogen receptor modulation
  • septate uterus
  • sexual dysfunction
  • sexually transmitted diseases
  • spontaneous abortion
  • squamous intraepithelial neoplasia
  • surgical staging
  • surgical sterilization
  • teratoma
  • teratoma of ovary
  • tubal ligation
  • tubal ligation reversal
  • tubo-ovarian abscess
  • unicorneate uterus
  • urethral cancer
  • urge incontinence
  • urinary retention
  • urinary stress incontinence
  • urinary tract infection
  • urinary urgency
  • uterine abnormality
  • uterine bleeding
  • uterine cancer
  • uterine fibroid embolization counseling
  • uterine lining removal
  • uterine myoma
  • uterine polyp
  • uterine prolapse
  • uterine surgery
  • uterovaginal prolapse
  • vaginal abscess
  • vaginal atrophy
  • vaginal biopsy
  • vaginal birth after caesarean section
  • vaginal bleeding
  • vaginal bleeding after hysterectomy
  • vaginal candidiasis
  • vaginal discharge
  • vaginal hysterectomy
  • vaginal infections
  • vaginal intraepithelial neoplasia
  • vaginal irritation
  • vaginismus
  • vaginitis
  • vasomotor symptoms
  • vulvar abscess
  • vulvar cancer
  • vulvar disease
  • vulvar dysplasia
  • vulvar vestibulitis
  • vulvodynia
  • vulvovaginitis
  • water birth
  • water birth information
  • women's health


Dr. Pamela Paley is the lead investigator for the following clinical trials currently available at the Swedish Medical Center:

Investigating the Use of Fluorescence Imaging in Endometrial Cancer Surgery

Ovarian Cancer Early Protection Program


McGonigle KF, Muntz HG, Vuky J, Paley PJ, Veljovich DS, Greer BE, Goff BA, Gray HJ, Malpass TW. Combined weekly topotecan and biweekly bevacizumab in women with platinum-resistant ovarian, peritoneal, or fallopian tube cancer: results of a phase 2 study. Cancer. 2011 Aug 15;117(16):3731-40. doi: 10.1002/cncr.25967. Epub 2011 Feb 24.

Thrall MM, Paley P, Pizer E, Garcia R, Goff BA. Patterns of spread and recurrence of sex cord-stromal tumors of the ovary. Gynecol Oncol. 2011 Aug;122(2):242-5. Epub 2011 Apr 9.

Paley PJ, Veljovich DS, Shah CA, Everett EN, Bondurant AE, Drescher CW, Peters WA 3rd. Surgical outcomes in gynecologic oncology in the era of robotics: analysis of first 1000 cases. Am J Obstet Gynecol. 2011 Jun;204(6):551.e1-9. Epub 2011 Mar 16.

Andersen MR, Goff BA, Lowe KA, Scholler N, Bergan L, Drescher CW, Paley P, Urban N. Use of a Symptom Index, CA125, and HE4 to predict ovarian cancer. Gynecol Oncol. 2010 Mar;116(3):378-83. Epub 2009 Nov 28.

Lowe KA, Andersen MR, Urban N, Paley P, Dresher CW, Goff BA. The temporal stability of the Symptom Index among women at high-risk for ovarian cancer. Gynecol Oncol. 2009 Aug;114(2):225-30. Epub 2009 May 7.

Shah CA, Lowe KA, Paley P, Wallace E, Anderson GL, McIntosh MW, Andersen MR, Scholler N, Bergan LA, Thorpe JD, Urban N, Drescher CW. Influence of ovarian cancer risk status on the diagnostic performance of the serum biomarkers mesothelin, HE4, and CA125. Cancer Epidemiol Biomarkers Prev. 2009 May;18(5):1365-72.

Lowe KA, Shah C, Wallace E, Anderson G, Paley P, McIntosh M, Andersen MR, Scholler N, Bergan L, Thorpe J, Urban N, Drescher CW. Effects of personal characteristics on serum CA125, mesothelin, and HE4 levels in healthy postmenopausal women at high-risk for ovarian cancer. Cancer Epidemiol Biomarkers Prev. 2008 Sep;17(9):2480-7.

Andersen MR, Goff BA, Lowe KA, Scholler N, Bergan L, Dresher CW, Paley P, Urban N. Combining a symptoms index with CA 125 to improve detection of ovarian cancer. Cancer. 2008 Aug 1;113(3):484-9.

Veljovich DS, Paley PJ, Drescher CW, Everett EN, Shah C, Peters WA 3rd. Robotic surgery in gynecologic oncology: program initiation and outcomes after the first year with comparison with laparotomy for endometrial cancer staging. Am J Obstet Gynecol. 2008 Jun;198(6):679.e1-9; discussion 679.e9-10.

Shah C, Pizer E, Veljovich DS, Drescher CW, Peters WA 3rd, Paley PJ. Clear cell adenocarcinoma of the vagina in a patient with vaginal endometriosis. Gynecol Oncol. 2006 Dec;103(3):1130-2. Epub 2006 Sep 22.

Lamb JD, Garcia RL, Goff BA, Paley PJ, Swisher EM. Predictors of occult neoplasia in women undergoing risk-reducing salpingo-oophorectomy. Am J Obstet Gynecol. 2006 Jun;194(6):1702-9.

Judson PL, Jonson AL, Paley PJ, Bliss RL, Murray KP, Downs LS Jr, Boente MP, Argenta PA, Carson LF. A prospective, randomized study analyzing sartorius transposition following inguinal-femoral lymphadenectomy. Gynecol Oncol. 2004 Oct;95(1):226-30.

Everett E, Tamimi H, Greer B, Swisher E, Paley P, Mandel L, Goff B. The effect of body mass index on clinical/pathologic features, surgical morbidity, and outcome in patients with endometrial cancer. Gynecol Oncol. 2003 Jul;90(1):150-7.

Stone B, Schummer M, Paley PJ, Thompson L, Stewart J, Ford M, Crawford M, Urban N, O'Briant K, Nelson BH. Serologic analysis of ovarian tumor antigens reveals a bias toward antigens encoded on 17q. Int J Cancer. 2003 Mar 10;104(1):73-84.

Goff BA, Sallin J, Garcia R, VanBlaricom A, Paley PJ, Muntz HG. Evaluation of p27 in preinvasive and invasive malignancies of the cervix. Gynecol Oncol. 2003 Jan;88(1):40-4.

Leeper K, Garcia R, Swisher E, Goff B, Greer B, Paley P. Pathologic findings in prophylactic oophorectomy specimens in high-risk women. Gynecol Oncol. 2002 Oct;87(1):52-6.

Gray HJ, Garcia R, Tamimi HK, Koh WJ, Goff BA, Greer BE, Paley PJ. Glassy cell carcinoma of the cervix revisited. Gynecol Oncol. 2002 May;85(2):274-7.

Paley PJ. Angiogenesis in ovarian cancer: molecular pathology and therapeutic strategies. Curr Oncol Rep. 2002 Mar;4(2):165-74.

Paley PJ. Ovarian cancer screening: are we making any progress? Curr Opin Oncol. 2001 Sep;13(5):399-402.

Stone B, Schummer M, Paley PJ, Crawford M, Ford M, Urban N, Nelson BH. MAGE-F1, a novel ubiquitously expressed member of the MAGE superfamily. Gene. 2001 Apr 18;267(2):173-82.

Paley PJ. Screening for the major malignancies affecting women: current guidelines. Am J Obstet Gynecol. 2001 Apr;184(5):1021-30.

Goff BA, Paley PJ, Greer BE, Gown AM. Evaluation of chemoresistance markers in women with epithelial ovarian carcinoma. Gynecol Oncol. 2001 Apr;81(1):18-24.

Paley PJ, Swisher EM, Garcia RL, Agoff SN, Greer BE, Peters KL, Goff BA. Occult cancer of the fallopian tube in BRCA-1 germline mutation carriers at prophylactic oophorectomy: a case for recommending hysterectomy at surgical prophylaxis. Gynecol Oncol. 2001 Feb;80(2):176-80.

Paley PJ, Goff BA, Gown AM, Greer BE, Sage EH. Alterations in SPARC and VEGF immunoreactivity in epithelial ovarian cancer. Gynecol Oncol. 2000 Sep;78(3 Pt 1):336-41.

Jain T, VanKessel K, Reed S, Paley P. Leydig cell tumor, mature teratoma, and nongestational choriocarcinoma in a single ovary. Obstet Gynecol. 2000 Jun;95(6 Pt 2):1031.

Paley PJ, Goff BA, Minudri R, Greer BE, Tamimi HK, Koh WJ. The prognostic significance of radiation dose and residual tumor in the treatment of barrel-shaped endophytic cervical carcinoma. Gynecol Oncol. 2000 Mar;76(3):373-9.

Horowitz NS, Tamimi HK, Goff BA, Koh WJ, Schmidt RA, Greer BE, Paley PJ. Pretreatment scalene node biopsy in gynecologic malignancy: prudent or pass�? Gynecol Oncol. 1999 Nov;75(2):238-41.

Goff BA, Muntz HG, Paley PJ, Tamimi HK, Koh WJ, Greer BE. Impact of surgical staging in women with locally advanced cervical cancer. Gynecol Oncol. 1999 Sep;74(3):436-42.

Paley PJ, Koh WJ, Stelzer KJ, Goff BA, Tamimi HK, Greer BE. A new technique for performing Syed template interstitial implants for anterior vaginal tumors using an open retropubic approach. Gynecol Oncol. 1999 Apr;73(1):121-5.

Cosin JA, Fowler JM, Chen MD, Paley PJ, Carson LF, Twiggs LB. Pretreatment surgical staging of patients with cervical carcinoma: the case for lymph node debulking. Cancer. 1998 Jun 1;82(11):2241-8.

Chen MD, Paley PJ, Potish RA, Twiggs LB. Phase I trial of taxol as a radiation sensitizer with cisplatin in advanced cervical cancer. Gynecol Oncol. 1997 Nov;67(2):131-6.

Paley PJ, Staskus KA, Gebhard K, Mohanraj D, Twiggs LB, Carson LF, Ramakrishnan S. Vascular endothelial growth factor expression in early stage ovarian carcinoma. Cancer. 1997 Jul 1;80(1):98-106.

Cosin JA, Carter JR, Paley P, Chen MD, Johnson P, Fowler JM, Twiggs LB, Carson LF. A simplified method for detubularization in the construction of a continent ileocolic reservoir (Miami pouch). Gynecol Oncol. 1997 Mar;64(3):436-41

Paley PJ, Johnson PR, Adcock LL, Cosin JA, Chen MD, Fowler JM, Twiggs LB, Carson LF. The effect of sartorius transposition on wound morbidity following inguinal-femoral lymphadenectomy. Gynecol Oncol. 1997 Feb;64(2):237-41.

Paley PJ, Johnson PR, Adcock LL, Cosin JA, Chen MD, Fowler JM, Twiggs LB, Carson LF. The effect of sartorius transposition on wound morbidity following inguinal-femoral lymphadenectomy. Gynecol Oncol. 1997 Feb;64(2):237-41.

Swedish Cancer Institute Gynecologic Oncology and Pelvic Surgery
751 Northeast Blakely Drive Floor 3
Issaquah, WA 98029
Swedish Cancer Institute Gynecologic Oncology and Pelvic Surgery
1101 Madison Street Suite 1500
Seattle, WA 98104
Pacific Gynecology Specialists - Providence Regional Cancer Center Lacey
4525 3rd Avenue Southeast Suite 200
Lacey, WA 98503
Pacific Gynecology Specialists - The Pavilion Bellevue
1231 116th Avenue Northeast Suite 525
Bellevue, WA 98004
Pacific Gynecology Specialists - Evergreen Specialty Clinic
12303 Northeast 130th Lane Suite 450
Kirkland, WA 98034
Affiliated Facilities
Swedish Issaquah
Swedish Cherry Hill
Swedish First Hill