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Henry G. Kaplan, MD

Languages: English
Accepting New Patients
Professional Statement
Dr. Kaplan is a 2017 Seattle Met Top Doctor Award winner. Philosophy of care: Try to help the patient make the most of life.
Field of Study
University of Rochester School of Medicine and Dentistry
Medical School
University of Washington School of Medicine
Internal Medicine, Oncology
University of Washington School of Medicine
Internal Medicine, Oncology
University of Washington School of Medicine
National Cancer Institute/National Institutes of Health - Clinical Associate
Professional Associations
Personal Interests
hiking, backpacking, photography
Board Certifications
  • American Board of Internal Medicine, Oncology
  • American Board of Internal Medicine, Internal Medicine
Clinical Interests
  • abnormal mammogram
  • amyloidosis
  • anemia
  • aromatase inhibitor
  • b12 deficiency anemia
  • blood cancer
  • bone marrow transplant
  • bone tumor
  • breast cancer
  • breast cancer chemotherapy
  • breast cancer follow up
  • breast cancer genetics
  • breast cancer genomics
  • cancer
  • cancer chemotherapy
  • cancer during pregnancy
  • cancer genomics
  • cancer survivorship
  • carcinoma in situ of breast
  • colorectal malignancy
  • dysplasia of breast
  • egfr mutation
  • endocrine complications of cancer therapy
  • er positive breast cancer
  • family history of breast cancer
  • head and neck cancer care
  • hellp syndrome
  • hemochromatosis
  • hemolytic uremic syndrome
  • heparin induced thrombocytopenia
  • herceptin
  • hereditary spherocytosis
  • histiocytosis
  • hormone replacement therapy
  • hypogammaglobulinemia
  • idiopathic thrombocytopenic purpura
  • iron deficiency anemia
  • leukemia
  • leukopenia
  • lymphoma
  • male breast cancer
  • mammogram
  • maternal hematologic disorders
  • metastatic breast cancer
  • microcalcifications
  • multiple myeloma
  • myelodysplasia
  • myelodysplastic syndrome
  • neutropenia
  • pancytopenia
  • paroxysmal nocturnal hemoglobinuria
  • petechiae
  • plasma cell dyscrasia
  • polycythemia
  • pulmonary metastases
  • purpura
  • radiation treatment for breast cancer
  • renal cancer
  • rh incompatibility
  • sarcoma
  • secondary polycythemia
  • sentinel node biopsy
  • splenomegaly
  • teratogen exposure
  • testicular cancer
  • thalassemia
  • thrombocytopenia
  • thrombophilia
  • thrombotic thrombocytopenic purpura
  • unknown primary cancer


Dr. Henry Kaplan is the lead investigator for the following clinical trials currently available at the Swedish Cancer Institute:

I-SPY 2 Trial (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis 2)

"PRESENT": Prevention of Recurrence in Early-Stage, Node-Positive Breast Cancer with Low to Intermediate HER2 Expression with NeuVax™ Treatment



Ryu RJ, Eyal S, Kaplan HG, Akbarzadeh A, Hays K, Puhl K, Easterling TR, Berg SL, Scorsone KA, Feldman EM, Umans JG, Miodovnik M, Hebert MF. Ryu RJ, Eyal S, Kaplan HG, Akbarzadeh A, Hays K, Puhl K, Easterling TR, Berg SL, Scorsone KA, Feldman EM, Umans JG, Miodovnik M, Hebert MF. Pharmacokinetics of doxorubicin in pregnant women.  Cancer Chemother Pharmacol. 2014 Apr; 73(4):789-97.
Kaplan HG. Vemurafenib treatment of BRAF V600E-mutated malignant peripheral nerve sheath tumor  J Natl Compr Canc Netw. 2013 Dec 1;11 (12):1466-70.
Kaplan HG, Malmgren JA, Li CI, Calip GS. Age related risk of myelodysplastic syndrome and acute myeloid leukemia among breast cancer survivors. Breast Cancer Res Treat. 2013 Dec; 142(3):629-36.
Kaplan HG, Malmgren JA, Atwood MK.  Adjuvant chemotherapy and differential invasive breast cancer specific survival in elderly women. J Geriatr Oncol. 2013 Apr;4(2):148-56. doi: 10.1016/j.jgo.2012.12.007. Epub 2013 Jan 23.
Nassiri F, Scheithauer BW, Corwin DJ, Kaplan HG, Mayberg M, Cusimano MD, Rotondo F, Kovacs K.  Invasive thymoma metastatic to the cavernous sinus. Surg Neurol Int. 2013 Jun 1;4:74.
Kaplan HG, Malmgren JA. The breast cancer overdiagnosis conundrum: an oncologist's viewpoint. Ann Intern Med. 2013 Jan 1;158(1):60-1.
Yee D, Haddad T, Albain K, Barker A, Benz C, Boughey J, Buxton M, Chien AJ, DeMichele A, Dilts D, Elias A, Haluska P, Hogarth M, Hu A, Hytlon N, Kaplan HG, Kelloff GG, Khan Q, Lang J, Leyland-Jones B, Liu M, Nanda R, Northfelt D, Olopade OI, Park J, Parker B, Parkinson D, Pearson-White S, Perlmutter J, Pusztai L, Symmans F, Rugo H, Tripathy D, Wallace A, Wholley D, Van't Veer L, Berry DA, Esserman L. Adaptive trials in the neoadjuvant setting: a model to safely tailor care while accelerating drug development. J Clin Oncol. 2012 Dec 20;30(36):4584-6. 

Malmgren JA, Parikh J, Atwood MK, KAPLAN HG. Impact of mammography detection on the course of breast cancer in women aged 40-49 years. Radiology. 2012 Mar; 262(3):797-806.

KAPLAN, H.G., Malmgren, J.A., and Atwood, M.K.: “Increased Incidence of Myelodysplastic Syndrome and Acute Myeloid Leukemia Following Breast Cancer Treatment with Radiation Alone or In Combination with Chemotherapy: A Registry Cohort Analysis 1990-2005,” BMC Cancer 11:260; 2011.

Malmgren, J.A., Atwood, M.K., and KAPLAN, H.G.: “Mammography Detected Breast Cancer Over Time Among Patients 75 and Older at a Community Based Cancer Center:1990-2008,” Amer Soc Clin Onc, 29(15S):#9086;2011.

KAPLAN, H.G., Malmgren, J.A., Atwood, M, Goldstein, L.C.: “Positive Response to Neoadjuvant Cyclophosphamide and Doxorubicin in Topoisomerase II Non-Amplified/Her2/neu negative/Polysomy 17 Absent Breast Cancer Patients,” Cancer Mgmt & Res, 2:213-218;2010.

KAPLAN, H.G., Malmgren, J.A., and Atwood, M.: “T1N0 Triple Negative Breast Cancer: Risk Recurrence and Adjuvant Chemotherapy,” Breast J 15(5):454-460; 2009.

Witzig, T.E., Wiernik, P.H., Moore, T., Reeder, C., Coe, C., Justice, G., KAPLAN, H., Voralia, M., Pietronigro, D., Takeshita, K., Ervin-Hayes, A., Zeldis, J.B., and Vose, J.M.: “Phase II Multi-Center Study of Lenalidomide Oral Monotherapy in Relapsed or Refractory Indolent Non-Hodgkin’s Lymphoma,” J Clin Onc, 27(32):5404-9;2009.

Malmgren, J.A., Atwood, M., and KAPLAN, H.: “Increase in Mammography Detected Breast Cancer Over Time at a Community Based Regional Cancer Center: A Longitudinal Cohort Study, 1990 – 2005,” BMC Cancer 8:131-7;2008.

Vemulakonda, V.M., Lendvay, T.S., Shnorhavorian, M., Joyner, B.D., KAPLAN, H., Mitchell, M.E., and Grady, R.W.: “Metastatic Adenocarcinoma after Augmentation Gastrocystoplasty, J Urology 179(3):1094-7;2008.

KAPLAN, H.G., and Malmgren, J.A.: “Impact of Triple Negative Phenotype on Breast Cancer Prognosis,” Breast J 14(5):456-463;2008.

KAPLAN, H.G., Malmgren, J.A., and Atwood, M.: “Impact of Detection Method on the Course of Breast Cancer: Patient versus Mammography Detected,” Clin. Breast Cancer, 7(2):133-140;2006.

KAPLAN, H.G., Malmgren, J.A., and Atwood, M.: “Leukemia Incidence Post Primary Breast Cancer Treatment,” Cancer 101:1529-1536; 2004.

Perez, E., Navari, R.M., KAPLAN, H.G., Gralla, R.J., Grunberg, S.M., Palmer, R., and Fitts, D.: “Antiemetic Efficacy and Safety of Different Doses of Granisetron in Patients Receiving Platinum,” Support. Care Cancer 5:31; 1997.

Navari, R.M., KAPLAN, H.G., Gralla, R.J., Grunberg, S.M., Palmer, R., and Fitts, D.: “Efficacy and Safety of Granisetron, A Selective 5-HT3 Antagonist, In the Prevention of Nausea and Vomiting Induced by High Dose Platinum,” J. Clin. Oncol. 12:2204; 1994.

KAPLAN, H.G.: “Cancer Chemotherapy in the Elderly,” in Vestal, R., ed., Drug Therapy in the Elderly, Addis Press, Auckland, 1984, pp. 338-350.

Larson, E.B., Scott, D.H., and KAPLAN, H.G.: “Inadequate Medical Order Writing – A Source of Confusion and Increased Costs,” Western J. Med. 139:50; 1983.

Wiemann, M.C., Cummings, F.J., KAPLAN, H.G., Spermuli, E.N., Doolittle, C.H., and Calabresi, P.: “Clinical and Pharmacological Studies of Methotrexate-Minimal Leucovorin Rescue Plus 5-Fluorouracil,” Cancer Res. 42:3896; 1982.

KAPLAN, H.G., Appelbaum, F.R., Cheever, M.A., Greenberg, P.D., Wood, T., and Fefer, A.: “Treatment of Refractory Acute Non-Lymphocytic Leukemia with A Combination of Pyrazofuran and Cytosine Arabinoside,” Cancer Treat. Rep. 66:1397; 1982.

Fefer, A., Cheever, M.A., Greenberg, P.D., Appelbaum, F.R., Boyd, C.N., Buckner, C.D., KAPLAN, H.G., Ramberg, R., Sanders, J.E., Storb, R., and Thomas, E.D.: “Treatment of Chronic Granulocytic Leukemia with Chemoradiotherapy and Transplantation of Marrow from Identical Twins.” New England J. Med. 306:63; 1982.

Appelbaum, F.R., Fefer, A., Cheever, M.A., Buckner, C.D., Greenberg, P.D., KAPLAN, H.G., Storb, R., and Thomas, E.D.: “Treatment of Non-Hodgkin’s Lymphoma with Marrow Transplantation in Identical Twins,” Blood 58:509; 1981.

Larson, S.M., Weiden, P.L., Grunbaum, Z., KAPLAN, H.G., Rasey, J.S., Graham, M.M., Sale, G.E., Harp, G., and Williams, D.L.: “Positron Imaging Feasibility Studies II: Characteristics of 2-Deoxyglucose Uptake in Rodent and Canine Neoplasms,” J. Nucl. Med. 22:881; 1981.

Larson, S.M., Weiden, P.L., Grunbaum, Z., Rasey, J.S., KAPLAN, H.G., Graham, M.M., Harp, G., Sale, G.E., and Williams, D.L.: “Positron Imaging Feasibility Studies I: Characteristics of 3H-Thymidine Uptake in Rodent and Canine Neoplasms,” J. Nucl. Med. 22:875; 1981.

Fefer, A., Cheever, M.A., Thomas, E.D., Appelbaum, F.R., Buckner, C.D., Clift, R.A., Glucksberg, H., Greenberg, P.D., Johnson, F.L., KAPLAN, H.G., Sanders, J.E., and Storb, R.: “Bone Marrow Transplantation for Refractory Acute Leukemia in 34 Patients with Identical Twins,” Blood 57:421; 1981.
KAPLAN, H.G.: “Inhibition of Buttermilk Xanthine Oxidase by Folate Analogues And Derivatives,” Biochem. Pharmacol. 29:2135; 1980.

KAPLAN, H.G., and Doolittle, C.: “Hodgkin’s Disease Presenting as Steroid-Dependent Pancytopenia,” Cancer 45:3114; 1980.

KAPLAN, H.G., Bakken, J., Quadracci, L., and Schubach, W.: “Hepatitis Caused by Repeated Sniffing of Halothane,” Annals Int. Med. 97:797; 1979.

Cummings, F.J., Stoller, R.G., KAPLAN, H.G., and Calabresi, P.: “A Clincial Study of Pyrazofuran,” Cancer Treat. Rep. 63:1363; 1979.

Stoller, R.G., KAPLAN, H.G., Cummings, F.J., and Calabresi, P.: “A Clinical and Pharmacological Study of High-Dose Methotrexate with Minimal Leucovorin Rescue,” Cancer Res. 39:908; 1979.

KAPLAN, H.G., and Myers, C.E.: “Complex Inhibition of Thymidylate Synthetase By Aromatic Diamidines: Evidence for Both Rapid, Freely Reversible and Slowly Progressive Non-Equilibrium Inhibition,” J. Pharm. Exptl. Therap.201:554; 1977.

Friedman, J, KAPLAN, H., and Hall, J.: “The Jeune Syndrome (Asphyxiating Thoracic Dystrophy) in an Adult,” Amer. J. Med. 59:875; 1975.

Miller, D.R., and KAPLAN, H.G.: “Reduced NBT Dye Reduction in Phagocytes Of Patients Receiving Prednisone,” Pediatrics 45:861; 1970.


The Patient Rating score is based on responses given during the CAHPS Patient Experience Survey.Responses are measured on a 10 - point scale, with 10 being the best score. These scores are then translated to a 5 - point scale in order to display results in a 5 - star rating.Comments are also gathered from the same survey and displayed in their entirety with the exception of any language that may be considered slander, libel or contain private health information, which will be removed prior to publishing the comments.

4.9 out of 5 (328 Ratings, 50 Comments)


Dr. Kaplan has been my oncologist for 19 years. I trust his judgement and advice, and have the utmost confidence in him. He and his staff are always polite, concerned, friendly, and willing to take time with me- if needed. I have recommended him to many people and now call Dr. Kaplan when I need the recommendation of a good doctor in a new area of medicine for me.

Dr Kaplan is always wonderful at listening and providing explanations

I feel very fortunate to have Dr. Kaplan as my oncologist.

I am fortunate to have Dr. Kaplan as my doctor. I have full confidence in his skills and care.

LOVE Dr Kaplan!

never really sure how often I'm suppose to follow up

I have referred 2 folks and will continue to, but with less confiedence at the moment about the support staff and office experience

positive experience

BEST doctor I have ever had! He gives appropriate recommendations & always considers your concern/included your preferences in Rx/care - NEVER makes you feel guilty - Hopefully he's training residents. He's the last of his kind - genuine, knowledgeable, KIND.

Dr. Kaplan takes such good care of me. During this visit, I had my uncle with me and he kept commenting on how amazing Dr. Kaplan and all the staff were. I truly am appreciative of the kindness and professionalism they have continued to show me. I can't imagine care without Dr. Kaplan. He's the best doctor and person I know.

Dr. Kaplan is always the best doctor, friendly, listening to patient. He's just like a father to me. Thanks to doctor for all the care he provided through out all these years.

Dr. Kaplan has been terrific. I would and have recommended him to others. I can't think of any other provider who is as thorough, competent and willing to listen and explain my issues.

Dr. Kaplan is simply the best.

I couldn't ask for a more caring and wonderful doctor.

Dr. Henry Kaplan is an exceptional doctor. In addition to being incredibly smart and knowledgeable, his communication skills and extent to which he truly cares about his patients puts him in a category of his own.

Dr. Kaplan is simply the best!

Dr Kaplan is good about listening to concerns and being a partner in my health care

Henry Kaplan for President!

I requested to be moved to Dr. Kaplan's care after hearing about his care from another Swedish-associated provider. I was immediately at ease with his manner, comforted that he had looked at my case history in advance of the appointment, encouraged that he moved to direct conversations with others on my care team in order to find clarity in lab and pathology reports, and so thankful he took time to answer my questions and concerns including returning my phone call the same day, long after his workday might have concluded. The brief time and experience in his care has improved more confidence in the choices about my care moving forward. A confident patient mindset is not to be underestimated as healing begins with a positive patient outlook and hope. Thank you. [...]

Dr. Kaplan is outstanding in every regard!!!

Hank Kaplan is a great physician. Excellent both for his medical knowledge as well as his interacting with his patients.

I have total confidence and truly thankful for the care that Dr Kaplan and the entire staff have given me

I am very pleased with the care I receive with Dr. Kaplan.

I have seen Dr. Kaplan for over 25 years. I whole heartedly would recommend him to anyone needing an oncologist. He is caring, patient and hardworking.

Dr. Kaplan is an excellent physician. he is very good about explaining things and puts you at ease. he is very caring and compassionate.

Dr Kaplan is amazing. After [...] decided not to negotiate a new contract with Swedish, I opted to change my insurance to [...] so that I can continue to see him. He got me through breast cancer and I trust him to keep me healthy and if the worst happens and cancer returns, there is no one else I'd rather have in my corner.

[...] Dr. Kaplan is the best both in terms of knowledge and caring about his patients.

Dr. Kaplan is an exceptional doctor and a wonderful person.

My care with Dr. Kaplan and staff have been excellent!

Dr. Kaplan has been my primary care provider for over 20 years. He is an exceptional physician who has taken great care of me over the years. I like his positive proactive medical approach and strong emphasis on preventative care.

Dr. Henry Kaplan is the best!!!!!

I have to be certain to ask questions if I have any, since I don't think I get all the information. Not sure it would be reasonable to give a "dissertation" about every potential concern. Asking questions works and they are answered until I understand--I just need to ask!

best doc I have!

I have always had good experiences with Dr. Kaplan as well as emotional support when I was feeling concerned or depressed.

All I can say is Dr. Kaplan is the best Dr. I have.

I come prepared with my questions typed out. This provider, patiently, lets me go through my list and answers each question or concern so that I can understand.

Dr. Kaplan is the best.

I have recommended Dr. Kaplan when I felt appropriate.

Dr. Kaplan is an outstanding physician. His demeanor with patients is incomparable. His care and concern for my well-being, as well as his knowledge and experience are greatly appreciated. I have referred friends with breast cancer to Dr. Kaplan because I trust him so completely.

Everything the best....Dr. Kaplan is clearly at the TOP of his profession in EVERY way possible, particularly in his knowledge and compassion for his patients.....To me, this is EVERYTHING again, and I can't say it enough to people about this.....

Dr Kaplan is straightforward in telling you about lab results or if anything during the physical exam is a concern or warrants an immediate test.

I have known this provider for 16+ years and see him for F/U of my breast cancer (in remission) I also ask him questions re: other concerns - I was cranky and uncomfortable that day due to pain from a non-related surgery - He was patient, kind [...]


Dr. Kaplan is a fabulous oncologist and a kind, knowledgeable person.

Excellent experience all around.

I believe Dr. Kaplan is the best! That belief alone is good medicine.

Dr. Kaplan is a wonderful caring doctor.

my total experience has always been great, while on my infrequent check back dr visits.

Couldn't be happier!

These guys are the best there is and they are the ones that make me well when my body falters
True Family Women's Cancer Center - 5th Floor
1221 Madison Street Floor 5
Seattle, WA 98104
Center for Blood Disorders and Stem Cell Transplantation
1221 Madison Street Floor 10
Seattle, WA 98104
Affiliated Facilities
Swedish Cherry Hill
Swedish First Hill
Swedish Edmonds