Pancreas Transplant

Pancreas Transplant

Swedish’s Pancreas Transplant Team is dedicated to restoring patients requiring lifelong insulin therapy to their optimum health by combining individualized, patient-centered care with the latest advances in pancreas transplant technology, state of the art operating facilities, and highly skilled surgeons.

Most pancreas transplants are performed at the same time as kidney transplants in patients with diabetes or after the kidney transplantation. The Pancreas Transplant team works closely with the Kidney Transplant team to develop individualized and comprehensive solutions to patients requiring pancreas transplantation.

Patients with Type I diabetes who still have preserved kidney function but have severe complications from diabetes are also considered for pancreas alone transplantation.

What is the pancreas?

The pancreas is a glandular organ which performs 2 important functions to assist in the digestion of food.

  • The pancreas produces enzymes that are secreted into the bowels to help break down fat and protein during digestion.
  • The pancreas also produces hormones (insulin and glucagon) that are secreted to the bloodstream to regulate blood sugar.

The ability of the pancreas to produce these hormones is often adversely affected by pancreatic diseases, most often diabetes.

Pancreas Transplants

Pancreas Transplants are performed on patients with type 1 and occasionally type 2 diabetes and usually result in the elimination of insulin injections.

Pancreas transplants result in an improved quality of life for diabetics. In many cases insulin therapy is a suitable option. The Swedish Transplant Team can help you weigh the transplant and lifelong immunosuppression versus continuing insulin therapy and help you decide on the best course of action for your situation.

A pancreas transplant involves implanting a healthy pancreas (one that can produce insulin) into a person who has diabetes. Donor pancreases come from a person who has been declared brain dead but is still on life support.

Types of Pancreas Transplants

There are three main types of pancreas transplantation:

  • Pancreas transplant alone, for the patient with type 1 diabetes who usually has severe, frequent hypoglycemia, but adequate kidney function.
  • Simultaneous pancreas-kidney transplant (SPK), when the pancreas and kidney are transplanted simultaneously from the same deceased donor.
  • Pancreas-after-kidney transplant (PAK), when a cadaveric, or deceased, donor pancreas transplant is performed after the recipient has already had a kidney transplant. Much of these pancreas transplants are done when a recipient receives a kidney from a living donor and then waits for a pancreas to become available.

Pancreas transplants are usually performed in persons with type 1, or occasionally type 2 insulin-dependent diabetes. Patients often have advanced chronic renal failure, end-stage renal disease, and/or are on dialysis. Over 80% of pancreas transplants are performed at the same time that a recipient is receiving a kidney transplant.

Preparing for Transplant Surgery

For more information on how to prepare for pancreas transplant surgery, please see:

Surgery

The pancreas is a vital organ performing functions necessary to the digestion process. Failure of the donor pancreas would quickly cause diabetes but also difficulties with the digestion process. To safeguard against this complication, the recipient’s native pancreas is left in place and the new pancreas is attached in a different location. In the event of rejection of the new pancreas, the recipient’s old pancreas will continue to perform the functions vital to the digestion process.

Pancreas transplant surgery alone takes about 3-4 hours. Pancreas transplant surgery with kidney transplant takes about 8 hours.

For more information on pancreas transplant surgery, please see Transplant Surgery.

Discharge, Recovery, and Post Operative Care

For more information on discharge, recovery, and post operative care, please see:


Contact Information

Transplant Program
1101 Madison
First Hill Campus, Suite 200
Seattle, WA 98104
Phone: 206-386-3660 or 1-800-99ORGAN (1-800-996-7426)
Fax: 206-386-3644
8 a.m. - 5 p.m.

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