Pamela J. Paley, MD

  • Gynecological Oncology
Accepting New Patients
Pacific Gynecology at Swedish Issaquah
751 NE Blakely Drive
Suite 3020
Issaquah 98029
Pacific Gynecology Specialists
1101 Madison
Suite 1500
Seattle 98104
(206) 965-1700
(206) 965-1735

General Information

I provide exceptional and comprehensive treatment to women stricken with gynecologic cancers with a compassionate and caring approach. I enjoy the long-term partnerships made with my patients, and consider myself privileged to be able to help women confronted with cancer.
  • Gynecological Oncology
Education Background
Medical School: Stritch School of Medicine, Loyola University Chicago, 1990
Residency: Duke University
Fellowship: University of Minnesota
  • English
Personal Interests
I met my husband, Jon Paley, who is also a physician in the area, while in training at Duke University. We have two children, to whom we devote much of our time. We enjoy an active life and spend time boating, traveling and skiing in British Columbia.




Dr. Pamela Paley is the lead investigator for the following clinical trials currently available at the Swedish Medical Center:

Investigating the Use of Fluorescence Imaging in Endometrial Cancer Surgery

Ovarian Cancer Early Protection Program


McGonigle KF, Muntz HG, Vuky J, Paley PJ, Veljovich DS, Greer BE, Goff BA, Gray HJ, Malpass TW. Combined weekly topotecan and biweekly bevacizumab in women with platinum-resistant ovarian, peritoneal, or fallopian tube cancer: results of a phase 2 study. Cancer. 2011 Aug 15;117(16):3731-40. doi: 10.1002/cncr.25967. Epub 2011 Feb 24.

Thrall MM, Paley P, Pizer E, Garcia R, Goff BA. Patterns of spread and recurrence of sex cord-stromal tumors of the ovary. Gynecol Oncol. 2011 Aug;122(2):242-5. Epub 2011 Apr 9.

Paley PJ, Veljovich DS, Shah CA, Everett EN, Bondurant AE, Drescher CW, Peters WA 3rd. Surgical outcomes in gynecologic oncology in the era of robotics: analysis of first 1000 cases. Am J Obstet Gynecol. 2011 Jun;204(6):551.e1-9. Epub 2011 Mar 16.

Andersen MR, Goff BA, Lowe KA, Scholler N, Bergan L, Drescher CW, Paley P, Urban N. Use of a Symptom Index, CA125, and HE4 to predict ovarian cancer. Gynecol Oncol. 2010 Mar;116(3):378-83. Epub 2009 Nov 28.

Lowe KA, Andersen MR, Urban N, Paley P, Dresher CW, Goff BA. The temporal stability of the Symptom Index among women at high-risk for ovarian cancer. Gynecol Oncol. 2009 Aug;114(2):225-30. Epub 2009 May 7.

Shah CA, Lowe KA, Paley P, Wallace E, Anderson GL, McIntosh MW, Andersen MR, Scholler N, Bergan LA, Thorpe JD, Urban N, Drescher CW. Influence of ovarian cancer risk status on the diagnostic performance of the serum biomarkers mesothelin, HE4, and CA125. Cancer Epidemiol Biomarkers Prev. 2009 May;18(5):1365-72.

Lowe KA, Shah C, Wallace E, Anderson G, Paley P, McIntosh M, Andersen MR, Scholler N, Bergan L, Thorpe J, Urban N, Drescher CW. Effects of personal characteristics on serum CA125, mesothelin, and HE4 levels in healthy postmenopausal women at high-risk for ovarian cancer. Cancer Epidemiol Biomarkers Prev. 2008 Sep;17(9):2480-7.

Andersen MR, Goff BA, Lowe KA, Scholler N, Bergan L, Dresher CW, Paley P, Urban N. Combining a symptoms index with CA 125 to improve detection of ovarian cancer. Cancer. 2008 Aug 1;113(3):484-9.

Veljovich DS, Paley PJ, Drescher CW, Everett EN, Shah C, Peters WA 3rd. Robotic surgery in gynecologic oncology: program initiation and outcomes after the first year with comparison with laparotomy for endometrial cancer staging. Am J Obstet Gynecol. 2008 Jun;198(6):679.e1-9; discussion 679.e9-10.

Shah C, Pizer E, Veljovich DS, Drescher CW, Peters WA 3rd, Paley PJ. Clear cell adenocarcinoma of the vagina in a patient with vaginal endometriosis. Gynecol Oncol. 2006 Dec;103(3):1130-2. Epub 2006 Sep 22.

Lamb JD, Garcia RL, Goff BA, Paley PJ, Swisher EM. Predictors of occult neoplasia in women undergoing risk-reducing salpingo-oophorectomy. Am J Obstet Gynecol. 2006 Jun;194(6):1702-9.

Judson PL, Jonson AL, Paley PJ, Bliss RL, Murray KP, Downs LS Jr, Boente MP, Argenta PA, Carson LF. A prospective, randomized study analyzing sartorius transposition following inguinal-femoral lymphadenectomy. Gynecol Oncol. 2004 Oct;95(1):226-30.

Everett E, Tamimi H, Greer B, Swisher E, Paley P, Mandel L, Goff B. The effect of body mass index on clinical/pathologic features, surgical morbidity, and outcome in patients with endometrial cancer. Gynecol Oncol. 2003 Jul;90(1):150-7.

Stone B, Schummer M, Paley PJ, Thompson L, Stewart J, Ford M, Crawford M, Urban N, O'Briant K, Nelson BH. Serologic analysis of ovarian tumor antigens reveals a bias toward antigens encoded on 17q. Int J Cancer. 2003 Mar 10;104(1):73-84.

Goff BA, Sallin J, Garcia R, VanBlaricom A, Paley PJ, Muntz HG. Evaluation of p27 in preinvasive and invasive malignancies of the cervix. Gynecol Oncol. 2003 Jan;88(1):40-4.

Leeper K, Garcia R, Swisher E, Goff B, Greer B, Paley P. Pathologic findings in prophylactic oophorectomy specimens in high-risk women. Gynecol Oncol. 2002 Oct;87(1):52-6.

Gray HJ, Garcia R, Tamimi HK, Koh WJ, Goff BA, Greer BE, Paley PJ. Glassy cell carcinoma of the cervix revisited. Gynecol Oncol. 2002 May;85(2):274-7.

Paley PJ. Angiogenesis in ovarian cancer: molecular pathology and therapeutic strategies. Curr Oncol Rep. 2002 Mar;4(2):165-74.

Paley PJ. Ovarian cancer screening: are we making any progress? Curr Opin Oncol. 2001 Sep;13(5):399-402.

Stone B, Schummer M, Paley PJ, Crawford M, Ford M, Urban N, Nelson BH. MAGE-F1, a novel ubiquitously expressed member of the MAGE superfamily. Gene. 2001 Apr 18;267(2):173-82.

Paley PJ. Screening for the major malignancies affecting women: current guidelines. Am J Obstet Gynecol. 2001 Apr;184(5):1021-30.

Goff BA, Paley PJ, Greer BE, Gown AM. Evaluation of chemoresistance markers in women with epithelial ovarian carcinoma. Gynecol Oncol. 2001 Apr;81(1):18-24.

Paley PJ, Swisher EM, Garcia RL, Agoff SN, Greer BE, Peters KL, Goff BA. Occult cancer of the fallopian tube in BRCA-1 germline mutation carriers at prophylactic oophorectomy: a case for recommending hysterectomy at surgical prophylaxis. Gynecol Oncol. 2001 Feb;80(2):176-80.

Paley PJ, Goff BA, Gown AM, Greer BE, Sage EH. Alterations in SPARC and VEGF immunoreactivity in epithelial ovarian cancer. Gynecol Oncol. 2000 Sep;78(3 Pt 1):336-41.

Jain T, VanKessel K, Reed S, Paley P. Leydig cell tumor, mature teratoma, and nongestational choriocarcinoma in a single ovary. Obstet Gynecol. 2000 Jun;95(6 Pt 2):1031.

Paley PJ, Goff BA, Minudri R, Greer BE, Tamimi HK, Koh WJ. The prognostic significance of radiation dose and residual tumor in the treatment of barrel-shaped endophytic cervical carcinoma. Gynecol Oncol. 2000 Mar;76(3):373-9.

Horowitz NS, Tamimi HK, Goff BA, Koh WJ, Schmidt RA, Greer BE, Paley PJ. Pretreatment scalene node biopsy in gynecologic malignancy: prudent or pass�? Gynecol Oncol. 1999 Nov;75(2):238-41.

Goff BA, Muntz HG, Paley PJ, Tamimi HK, Koh WJ, Greer BE. Impact of surgical staging in women with locally advanced cervical cancer. Gynecol Oncol. 1999 Sep;74(3):436-42.

Paley PJ, Koh WJ, Stelzer KJ, Goff BA, Tamimi HK, Greer BE. A new technique for performing Syed template interstitial implants for anterior vaginal tumors using an open retropubic approach. Gynecol Oncol. 1999 Apr;73(1):121-5.

Cosin JA, Fowler JM, Chen MD, Paley PJ, Carson LF, Twiggs LB. Pretreatment surgical staging of patients with cervical carcinoma: the case for lymph node debulking. Cancer. 1998 Jun 1;82(11):2241-8.

Chen MD, Paley PJ, Potish RA, Twiggs LB. Phase I trial of taxol as a radiation sensitizer with cisplatin in advanced cervical cancer. Gynecol Oncol. 1997 Nov;67(2):131-6.

Paley PJ, Staskus KA, Gebhard K, Mohanraj D, Twiggs LB, Carson LF, Ramakrishnan S. Vascular endothelial growth factor expression in early stage ovarian carcinoma. Cancer. 1997 Jul 1;80(1):98-106.

Cosin JA, Carter JR, Paley P, Chen MD, Johnson P, Fowler JM, Twiggs LB, Carson LF. A simplified method for detubularization in the construction of a continent ileocolic reservoir (Miami pouch). Gynecol Oncol. 1997 Mar;64(3):436-41

Paley PJ, Johnson PR, Adcock LL, Cosin JA, Chen MD, Fowler JM, Twiggs LB, Carson LF. The effect of sartorius transposition on wound morbidity following inguinal-femoral lymphadenectomy. Gynecol Oncol. 1997 Feb;64(2):237-41.

Paley PJ, Johnson PR, Adcock LL, Cosin JA, Chen MD, Fowler JM, Twiggs LB, Carson LF. The effect of sartorius transposition on wound morbidity following inguinal-femoral lymphadenectomy. Gynecol Oncol. 1997 Feb;64(2):237-41.

Clinical Experience

  • Gynecological Oncology
Clinical Interests
  • Bilateral Salpingo-Oophorectomy (Laparoscopic)
  • Bilateral Salpingo-Oophorectomy (Robotic)
  • Bladder Procedures (Robotic)
  • Cervical Cancer
  • da Vinci (Robot-Assisted Surgery)
  • Endometrial Cancer
  • Endometriosis
  • Gynecologic Cancer Surgery (Robotic)
  • Gynecologic Oncologists
  • Gynecological Surgery
  • Gynecological Surgery (Robotic)
  • Hysterectomy (Robotic)
  • Hysterectomy Vaginal (Laparoscopic-assisted)
  • Myomectomy (Robotic)
  • Ovarian Cancer
  • Pelvic Prolapse
  • Sacrocolpopexy (Robotic)
  • Supracervical Hysterectomy - Laparoscopic
Pacific Gynecology at Swedish Issaquah
751 NE Blakely Drive
Suite 3020
Issaquah, 98029
Pacific Gynecology Specialists
1101 Madison
Suite 1500
Seattle, 98104
(206) 965-1735
Affiliated Facilities