Henry G. Kaplan, MD


Specialties
  • Medical Oncology
Accepting New Patients
1221 Madison St.
10th Floor
Seattle, WA 98104
206-991-2040
206-215-1655
1221 Madison St.
Arnold Pavilion, Suite 200
Seattle, WA 98104
1-855-XCANCER
1221 Madison St.
5th Floor
Seattle, WA 98104
1-855-XCANCER

General Information


Biography
Try to help the patient make the most of life
Specialties
  • Medical Oncology
Education Background
Medical School: University of Rochester School of Medicine and Dentistry, 1972
Internship: University of Washington School of Medicine, Internal Medicine, Oncology, 1973
Residency: University of Washington School of Medicine, Internal Medicine, Oncology, 1977
Fellowship: National Cancer Institute/National Institutes of Health - Clinical Associate
Fellowship: University of Washington School of Medicine, Oncology, 1977
Languages
  • English
Professional Associations
AOA, ASCO, AACR, ASBD, NS Society, AMA, WSMA
Personal Interests
hiking, backpacking, photography

Publications

Research

CLINICAL TRIALS:

Dr. Henry Kaplan is the lead investigator for the following clinical trials currently available at the Swedish Cancer Institute:

I-SPY 2 Trial (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis 2)

"PRESENT": Prevention of Recurrence in Early-Stage, Node-Positive Breast Cancer with Low to Intermediate HER2 Expression with NeuVax™ Treatment

________________________________________

PUBLICATIONS:

Ryu RJ, Eyal S, Kaplan HG, Akbarzadeh A, Hays K, Puhl K, Easterling TR, Berg SL, Scorsone KA, Feldman EM, Umans JG, Miodovnik M, Hebert MF. Ryu RJ, Eyal S, Kaplan HG, Akbarzadeh A, Hays K, Puhl K, Easterling TR, Berg SL, Scorsone KA, Feldman EM, Umans JG, Miodovnik M, Hebert MF. Pharmacokinetics of doxorubicin in pregnant women.  Cancer Chemother Pharmacol. 2014 Apr; 73(4):789-97.
 
Kaplan HG. Vemurafenib treatment of BRAF V600E-mutated malignant peripheral nerve sheath tumor  J Natl Compr Canc Netw. 2013 Dec 1;11 (12):1466-70.
 
Kaplan HG, Malmgren JA, Li CI, Calip GS. Age related risk of myelodysplastic syndrome and acute myeloid leukemia among breast cancer survivors. Breast Cancer Res Treat. 2013 Dec; 142(3):629-36.
 
Kaplan HG, Malmgren JA, Atwood MK.  Adjuvant chemotherapy and differential invasive breast cancer specific survival in elderly women. J Geriatr Oncol. 2013 Apr;4(2):148-56. doi: 10.1016/j.jgo.2012.12.007. Epub 2013 Jan 23.
 
Nassiri F, Scheithauer BW, Corwin DJ, Kaplan HG, Mayberg M, Cusimano MD, Rotondo F, Kovacs K.  Invasive thymoma metastatic to the cavernous sinus. Surg Neurol Int. 2013 Jun 1;4:74.
 
Kaplan HG, Malmgren JA. The breast cancer overdiagnosis conundrum: an oncologist's viewpoint. Ann Intern Med. 2013 Jan 1;158(1):60-1.
 
Yee D, Haddad T, Albain K, Barker A, Benz C, Boughey J, Buxton M, Chien AJ, DeMichele A, Dilts D, Elias A, Haluska P, Hogarth M, Hu A, Hytlon N, Kaplan HG, Kelloff GG, Khan Q, Lang J, Leyland-Jones B, Liu M, Nanda R, Northfelt D, Olopade OI, Park J, Parker B, Parkinson D, Pearson-White S, Perlmutter J, Pusztai L, Symmans F, Rugo H, Tripathy D, Wallace A, Wholley D, Van't Veer L, Berry DA, Esserman L. Adaptive trials in the neoadjuvant setting: a model to safely tailor care while accelerating drug development. J Clin Oncol. 2012 Dec 20;30(36):4584-6. 

Malmgren JA, Parikh J, Atwood MK, KAPLAN HG. Impact of mammography detection on the course of breast cancer in women aged 40-49 years. Radiology. 2012 Mar; 262(3):797-806.

KAPLAN, H.G., Malmgren, J.A., and Atwood, M.K.: “Increased Incidence of Myelodysplastic Syndrome and Acute Myeloid Leukemia Following Breast Cancer Treatment with Radiation Alone or In Combination with Chemotherapy: A Registry Cohort Analysis 1990-2005,” BMC Cancer 11:260; 2011.

Malmgren, J.A., Atwood, M.K., and KAPLAN, H.G.: “Mammography Detected Breast Cancer Over Time Among Patients 75 and Older at a Community Based Cancer Center:1990-2008,” Amer Soc Clin Onc, 29(15S):#9086;2011.

KAPLAN, H.G., Malmgren, J.A., Atwood, M, Goldstein, L.C.: “Positive Response to Neoadjuvant Cyclophosphamide and Doxorubicin in Topoisomerase II Non-Amplified/Her2/neu negative/Polysomy 17 Absent Breast Cancer Patients,” Cancer Mgmt & Res, 2:213-218;2010.

KAPLAN, H.G., Malmgren, J.A., and Atwood, M.: “T1N0 Triple Negative Breast Cancer: Risk Recurrence and Adjuvant Chemotherapy,” Breast J 15(5):454-460; 2009.

Witzig, T.E., Wiernik, P.H., Moore, T., Reeder, C., Coe, C., Justice, G., KAPLAN, H., Voralia, M., Pietronigro, D., Takeshita, K., Ervin-Hayes, A., Zeldis, J.B., and Vose, J.M.: “Phase II Multi-Center Study of Lenalidomide Oral Monotherapy in Relapsed or Refractory Indolent Non-Hodgkin’s Lymphoma,” J Clin Onc, 27(32):5404-9;2009.

Malmgren, J.A., Atwood, M., and KAPLAN, H.: “Increase in Mammography Detected Breast Cancer Over Time at a Community Based Regional Cancer Center: A Longitudinal Cohort Study, 1990 – 2005,” BMC Cancer 8:131-7;2008.

Vemulakonda, V.M., Lendvay, T.S., Shnorhavorian, M., Joyner, B.D., KAPLAN, H., Mitchell, M.E., and Grady, R.W.: “Metastatic Adenocarcinoma after Augmentation Gastrocystoplasty, J Urology 179(3):1094-7;2008.

KAPLAN, H.G., and Malmgren, J.A.: “Impact of Triple Negative Phenotype on Breast Cancer Prognosis,” Breast J 14(5):456-463;2008.

KAPLAN, H.G., Malmgren, J.A., and Atwood, M.: “Impact of Detection Method on the Course of Breast Cancer: Patient versus Mammography Detected,” Clin. Breast Cancer, 7(2):133-140;2006.

KAPLAN, H.G., Malmgren, J.A., and Atwood, M.: “Leukemia Incidence Post Primary Breast Cancer Treatment,” Cancer 101:1529-1536; 2004.

Perez, E., Navari, R.M., KAPLAN, H.G., Gralla, R.J., Grunberg, S.M., Palmer, R., and Fitts, D.: “Antiemetic Efficacy and Safety of Different Doses of Granisetron in Patients Receiving Platinum,” Support. Care Cancer 5:31; 1997.

Navari, R.M., KAPLAN, H.G., Gralla, R.J., Grunberg, S.M., Palmer, R., and Fitts, D.: “Efficacy and Safety of Granisetron, A Selective 5-HT3 Antagonist, In the Prevention of Nausea and Vomiting Induced by High Dose Platinum,” J. Clin. Oncol. 12:2204; 1994.

KAPLAN, H.G.: “Cancer Chemotherapy in the Elderly,” in Vestal, R., ed., Drug Therapy in the Elderly, Addis Press, Auckland, 1984, pp. 338-350.

Larson, E.B., Scott, D.H., and KAPLAN, H.G.: “Inadequate Medical Order Writing – A Source of Confusion and Increased Costs,” Western J. Med. 139:50; 1983.

Wiemann, M.C., Cummings, F.J., KAPLAN, H.G., Spermuli, E.N., Doolittle, C.H., and Calabresi, P.: “Clinical and Pharmacological Studies of Methotrexate-Minimal Leucovorin Rescue Plus 5-Fluorouracil,” Cancer Res. 42:3896; 1982.

KAPLAN, H.G., Appelbaum, F.R., Cheever, M.A., Greenberg, P.D., Wood, T., and Fefer, A.: “Treatment of Refractory Acute Non-Lymphocytic Leukemia with A Combination of Pyrazofuran and Cytosine Arabinoside,” Cancer Treat. Rep. 66:1397; 1982.

Fefer, A., Cheever, M.A., Greenberg, P.D., Appelbaum, F.R., Boyd, C.N., Buckner, C.D., KAPLAN, H.G., Ramberg, R., Sanders, J.E., Storb, R., and Thomas, E.D.: “Treatment of Chronic Granulocytic Leukemia with Chemoradiotherapy and Transplantation of Marrow from Identical Twins.” New England J. Med. 306:63; 1982.

Appelbaum, F.R., Fefer, A., Cheever, M.A., Buckner, C.D., Greenberg, P.D., KAPLAN, H.G., Storb, R., and Thomas, E.D.: “Treatment of Non-Hodgkin’s Lymphoma with Marrow Transplantation in Identical Twins,” Blood 58:509; 1981.

Larson, S.M., Weiden, P.L., Grunbaum, Z., KAPLAN, H.G., Rasey, J.S., Graham, M.M., Sale, G.E., Harp, G., and Williams, D.L.: “Positron Imaging Feasibility Studies II: Characteristics of 2-Deoxyglucose Uptake in Rodent and Canine Neoplasms,” J. Nucl. Med. 22:881; 1981.

Larson, S.M., Weiden, P.L., Grunbaum, Z., Rasey, J.S., KAPLAN, H.G., Graham, M.M., Harp, G., Sale, G.E., and Williams, D.L.: “Positron Imaging Feasibility Studies I: Characteristics of 3H-Thymidine Uptake in Rodent and Canine Neoplasms,” J. Nucl. Med. 22:875; 1981.

Fefer, A., Cheever, M.A., Thomas, E.D., Appelbaum, F.R., Buckner, C.D., Clift, R.A., Glucksberg, H., Greenberg, P.D., Johnson, F.L., KAPLAN, H.G., Sanders, J.E., and Storb, R.: “Bone Marrow Transplantation for Refractory Acute Leukemia in 34 Patients with Identical Twins,” Blood 57:421; 1981.
KAPLAN, H.G.: “Inhibition of Buttermilk Xanthine Oxidase by Folate Analogues And Derivatives,” Biochem. Pharmacol. 29:2135; 1980.

KAPLAN, H.G., and Doolittle, C.: “Hodgkin’s Disease Presenting as Steroid-Dependent Pancytopenia,” Cancer 45:3114; 1980.

KAPLAN, H.G., Bakken, J., Quadracci, L., and Schubach, W.: “Hepatitis Caused by Repeated Sniffing of Halothane,” Annals Int. Med. 97:797; 1979.

Cummings, F.J., Stoller, R.G., KAPLAN, H.G., and Calabresi, P.: “A Clincial Study of Pyrazofuran,” Cancer Treat. Rep. 63:1363; 1979.

Stoller, R.G., KAPLAN, H.G., Cummings, F.J., and Calabresi, P.: “A Clinical and Pharmacological Study of High-Dose Methotrexate with Minimal Leucovorin Rescue,” Cancer Res. 39:908; 1979.

KAPLAN, H.G., and Myers, C.E.: “Complex Inhibition of Thymidylate Synthetase By Aromatic Diamidines: Evidence for Both Rapid, Freely Reversible and Slowly Progressive Non-Equilibrium Inhibition,” J. Pharm. Exptl. Therap.201:554; 1977.

Friedman, J, KAPLAN, H., and Hall, J.: “The Jeune Syndrome (Asphyxiating Thoracic Dystrophy) in an Adult,” Amer. J. Med. 59:875; 1975.

Miller, D.R., and KAPLAN, H.G.: “Reduced NBT Dye Reduction in Phagocytes Of Patients Receiving Prednisone,” Pediatrics 45:861; 1970.

Clinical Experience

Reviews

Patient Ratings and Comments
 

The Patient Rating score is based on responses given during the CAHPS Patient Experience Survey. Responses are measured on a 10-point scale, with 10 being the best score. These scores are then translated to a 5-point scale in order to display results in a 5-star rating. Comments are also gathered from the same survey and displayed in their entirety with the exception of any language that may be considered slander, libel or contain private health information, which will be removed prior to publishing the comments.

4.9 out of 5 (365 Ratings, 66 Comments)

100

06/29/2016
I cannot say enough positives about the care I receive from Dr. Kaplan. He is not only extremely knowledgeable, but always makes me feel that I am involved in all medical decisions. I have only wonderful things to say about him and tell the same to family and friends.
100

06/14/2016
Dr. Kaplan is a marvelous doctor and a wonderful person. I have cancer, and I trust Dr. Kaplan completely in his decisions about my care.
90

06/08/2016
One of the best if not the best oncologist
100

05/29/2016
knowledgeable, thoughtful, encouraging and kind
100

05/26/2016
The very best!
100

05/13/2016
When ever I am asked by people about you I think they should see about medical problems, It is Dr Kaplan and the team at Swedish that I recommend. They are the best
100

05/08/2016
Dr Kaplan is the best oncologist available. I was very fortunate to get him. [...] I am very grateful to be his patient.
100

05/05/2016
Dr. Kaplan is an EXCELLENT provider and I highly recommend him!
100

04/26/2016
Hank Kaplan saved my wife from aggressive breast cancer [...]. She is fine 24 years later. He now keeps track of my [...]. There is no finer doctor in Seattle.
100

04/24/2016
good
100

04/21/2016
Dr. Kaplan is a very caring, concerned, thoughtful - especially wonderful doctor - Always has the time for you & a hug if you need it.
100

04/13/2016
KAPLAN HAS KEPT ME ALIVE FOR THE LAST 30 YRS
100

04/12/2016
Dr. Kaplan is wonderful. He makes going through Chemo much easier than it would be without his help.
100

04/12/2016
Dr Kaplin has always shown care and compassion for any question or concern my wife has had during my appointments
100

04/05/2016
Dr. Kaplan is the best!. I feel special. I feel listened to with understanding. I am spoken to with care and politeness. I feel very safe in the knowledge, care and treatment, received by Dr Kaplan and trust him completely! Thank you Swedish!
100

03/22/2016
Dr. Kaplan is THE BEST! He is the main reason that I am rarely stressed out, or nervous on my Mandatory ongoing follow-up visits. He is definitely part of my decision making process when considering the possibility of my moving out of the area.
100

03/22/2016
Dr. Kaplan is a brilliant, compassionate, funny, wonderful man. And I know I'm not his only patient who thinks so. His reputation in this city is absolutely phenomenal.
100

03/16/2016
Dr. Kaplan is exceptional. He is the most wonderful doctor.
100

03/15/2016
Dr Kaplan is the best.
100

03/10/2016
Dr. Kaplan is THE best! As a physician of over 30 yrs. , I can judge this objectively and as his patient for 8 yrs, I have more than adequate experience to judge. His other patients whom I have spoken to, feel the same. Oncology is a difficult and draining subspecialty; it is beyond me how he does what he does with no compromises visit after visit
100

03/08/2016
Love Dr. Kaplan! Have every confidence in him. He really cares.
50

03/01/2016
He is a good doctor, kind and friendly but the process in his office is poor. The care plan review is loose as the "hold" of patient case. wouldn't recommend it to a friend that can not advocate for themselves.
100

03/01/2016
Thank goodness for Dr. Kaplan, I have referred him to others.
100

02/29/2016
Always helpful
100

02/28/2016
Dr. Kaplan is beyond what I could have hoped for. He is an excellent physician with a wonderful bedside manner. I could not ask for a better doctor.
100

02/23/2016
Dr. Kaplan is one of the top oncologists. He has been vigilant about my care since I first entered his office over a year ago. He patiently answers all questions. He explains things in a way I can understand. He takes immediate action if necessary. He is kind and empathetic. He responds to all email messages--in the early am hours. He inspires confidence.
100

02/21/2016
Dr. Kaplan and staff are the absolute BEST! I recommend Kaplan's team and the entire Swedish experience to all.
100

02/21/2016
Dr. Kaplan is competent, caring and calming.
100

02/09/2016
I love Hank Kaplan!!!
100

02/09/2016
Dr. Kaplan does in fact walk on water
100

02/09/2016
doctor kaplan is top notch, seems to genuinely care about his patients
100

02/09/2016
I can only give Dr. Henry Kaplan the highest of marks for the care and understanding he has given me. He is a very compassionate doctor. He is the best!
100

01/27/2016
Dr. Kaplan is the most caring, kind and concerned doctor that it has been my privilege to be associated with over the years.
100

01/27/2016
Dr. Kaplan is the most amazing doctor I have ever received care from, although I wish it could have been under different circumstances. From my diagnosis to surgery and radiation therapy, Dr. Kaplan has been awesome through it all. He has given me his utmost attention and made the care he provides very personal. I would HIGHLY recommend him to anyone that is diagnosed with cancer.
100

01/17/2016
Dr Kaplan is the best doctor I have ever hadHe treats each patient as an individual and answers every question at any time of day or night! does not delegate everything to staff. he does it himself.
100

01/12/2016
Awesome staff and doctor.
100

01/06/2016
I most definitely would recommend Dr. Kaplan to others!
100

12/31/2015
Dr. Kaplan is an extraordinarily doctor.
100

12/29/2015
Dr. Kaplan, his team, and the people at Swedish are top notch!
100

12/28/2015
Dr. Kaplan is an excellent clinician & an asset to our medical community.
100

12/11/2015
Dr. Kaplan is amazing. I couldn't ask for a better cancer doctor. He is warm,compassionate and very knowledgeable. I have been very fortunate to have such a wonderful doctor.
100

11/29/2015
I have seen many doctors over the years, and without question, Dr. Kaplan is exemplary. From our first meeting, I knew I had found the best. He put my husband and me at ease with his caring manner and thorough plan for my treatment. His warm personality and keen intellect combined with years of experience helped me to relax and trust in his care. A friend recommended Dr. Kaplan to me, and I, in turn, have recommended him to others. He is an amazing physician.
100

11/24/2015
Dr. Kaplan is everything you hope a doctor would be...kind, smart, funny, and caring.
100

11/24/2015
Dr. Kaplan is the best physician I have seen
90

11/22/2015
I know, from my research, that Dr Kaplan is highly respected and considered one of the best oncologists in Seattle.
100

11/17/2015
my current visits with Dr Kaplan are now an annual checkup as I'm no longer being treated for breast cancer. it's always a pleasure and JOY to see him in person!
100

11/12/2015
The Best!
100

11/11/2015
Dr. Kaplan is an outstanding doctor -- the very best.
100

11/09/2015
Dr. Kaplan was absolutely awesome. I had heard great things about him prior to my appointment with him, and he definitely lived up to his reputation. He showed sincere interest in my health care and about me personally. He is unlike any doctor I have ever had, and I would recommend him to friends, family, and strangers in a heartbeat.
 

11/03/2015
Dr. Kaplan is the best. He takes time to review my health staff and is thorough, professional,sympathic and efficient in his use of time. Awesome demeanor for a Dr in his field. Highly....highly recommend to anyone looking for an Oncologist. Simply the best in his field, bar none!
100

11/02/2015
Dr. Kaplan is a gem.
100

11/01/2015
Dr. Kaplan is always focused, kind, informative, and helpful.
100

10/27/2015
Dr. Kaplan is exceptional. He is an especially good listener.
100

10/27/2015
Dr. Kaplan is always great--I never feel like he's in a hurry, though I know he's busy, and he listens well, advises carefully.
100

10/25/2015
Dr. Kaplan, his staff & Swedish are tops - Dr. Kaplan is excellent!
100

10/20/2015
Dr. Kaplan is outstanding. I have complete trust in him, and enjoy my visits. He also is concerned about me and truly cares.
100

10/11/2015
There are not enough words to describe what a great doctor Dr. Kaplan is. He is so knowledgeable and kind and a great listener. I always leave feeling confident that he is watching out for my health.
100

10/06/2015
Dr. Kaplan is the best! Competent, respectful, patient, kind, resourceful.
100

09/22/2015
All around great experience. I am extremely pleased with my treatment, after-care and concern for my well-being.
100

08/30/2015
Dr. Kaplan is an outstanding Dr. with an exceptional bedside manner. I always feel very cared for and supported by him. I don't know how he continually gives so much emotionally and I appreciate that he does. I trust him and respect his deep medical knowledge as well as his emotions intelligence.
100

08/28/2015
Great doctor!
100

08/26/2015
Dr. Kaplan is perhaps the best doctor I have ever worked with. He remembered me from my last appt with him 3 YEARS ago, and is so incredibly personable and friendly, never condescending or hurried. He is amazing. I wish he could be my regular doctor.
100

08/25/2015
Dr. Kaplan is always the professional and I have respect for him.
100

08/23/2015
Dr Kaplan is an AMAZING provider, please keep him happy!!!!
100

08/12/2015
Dr. Kaplan is an unbelievably wise, knowledgeable and caring oncologist.
100

08/11/2015
I'm thankful every day that Dr. Kaplan was recommended to me. He's the best!
1221 Madison St.
10th Floor
Seattle, WA 98104
206-215-1655
1221 Madison St.
Arnold Pavilion, Suite 200
Seattle, WA 98104
1221 Madison St.
5th Floor
Seattle, WA 98104
Affiliated Facilities