John K. Hsiang, MD, PhD

  • Spine Surgery
  • Neurological Surgery
Accepting New Patients
751 NE Blakely Drive
4th Floor
Issaquah, WA 98029
751 NE Blakely Drive
Suite 4020, 4th Floor
Issaquah, WA 98209
(425) 313-7077
(425) 313-7180

General Information

Dr. Hsiang specializes in the surgical treatment of complex spinal disorders with an interest in minimally invasive spine surgery, including spine endoscopy. Dr. Hsiang sees patients experiencing pain caused by spinal degeneration and his focus is on nonsurgical treatment options first, believing surgery should be considered as a last resort. With a team approach to care, Dr. Hsiang works to relieve the symptoms and improve the quality of life for his patients. In practicing medicine, Dr. Hsiang submits himself to this guideline for patient care: "If this was my loved one, what would I do.
  • Neurological Surgery
  • Spine Surgery
Education Background
Medical School: University of Chicago Division of the Biological Sciences The Pritzker School of Medicine, 1988
Residency: UC San Diego Medical Center
  • English
  • Chinese - Cantonese
  • Chinese - Mandarin




CerviCore, Cervical Artificial Disc Clinical Trial Sponsored by Stryker Spine.

TFAS, Artificial Facet Joint Clinical Trial Sponsored by Archus Orthopedics.

AOI, Balloon Kyphoplasty Trial.

Randomized Controlled Trial of DuraGen Plus Adhesion Barrier Matrix to Minimize Adhesions Following Lumbar Disectomy.

NuVasive Osteocel Bone Graft for Anterior Cervical Fusion


Ph.D. Thesis

Hsiang J. "The study of neurotrophic effects of hippocampal target cells on developing septal cholinergic neurons in reaggregate cultures." Department of Pathology, The University of Chicago. 1986.

Book Chapter

Hsiang J and Marshall LF. "Trauma to the CNS: Head Injury." in Swash and Wilden (ed): Outcomes in Neurological and Neurosurgical Disorders. Cambridge University Press. 1998 .


Hsiang JN, Furman MB, Keenan ME, et al. Spinal Stenosis. eMedicine from WebMD. Updated March 29, 2011. Available at:


Hsiang J, Wainer BH, Heller A, et al. "The influence of target and nontarget cells on the development of septal cholinergic neurons." Soc. for Neurosci. Abst. 11: 1147, 1985.

Wainer BH, Hsiang J, Price SD, et al. "Ultrastructural evidence for target cell-mediated trophic effects on cholinergic neurons in reaggregating cell cultures." Soc. for Neurosci. Abst. 12: 586, 1986.

Wainer BH, Hsiang J, Hoffmann PC, et al. "Nerve growth factor enhances central cholinergic cell survival and fiber proliferation in reaggregate culture." Abstracts of the 10th European Neuroscience Meeting. Neurosci. Letters (suppl) 26: 17, 1986.

Hsiang J, Chesnut RM, Crisp CB, et al. "Paralysis for intracranial pressure control in severe head injury: is it necessary?" Abst. of the 22nd Society of Critical Care Medicine Symposium. Critical Care Medicine (suppl) 21(4): S236, 1993.

Hsiang J, Cheung T, Poon WS. “Epidemiology of head injury in Hong Kong” Abst. of the 3rd. International Neurotrauma Symposium. J of Neurotrauma 12: 407, 1995

Lam J, Hsiang J, Poon WS. “Autoregulation monitoring using laser-doppler flowmetry on patients with head injury” Abst. of the 3rd. International Neurotrauma Symposium. J of Neurotrauma 12: 373, 1995

Hsiang J. “New trend of pathophysiology of head injury.” Presented at the 9th Asian-Australasian Congress of Neurological Surgery. Taipei, Nov. 1995

Choi KY, Poon WS, Hsiang J. “Clinical application of botulinum toxin in the prevention of spastic joint contracture in neurosurgical patients” Abst. presented at the annual congress of Western Pacific Orthopedic Association. Nov. 1995

Hsiang J. “Vagus Nerve Stimulation for Intractable Epilepsy Control.” Presented at the First Asian Epilepsy Symposium. Hong Kong, April 1996.

Hsiang J. “The Time Course and Regional Variations of Lipid Peroxidation after Diffuse Brain Injury in Rats.” Abst. presented at the ICRAN’96. Italy, Sept. 1996.

Hsiang J. “CerviCore-Cervical Artificial Disc: Preliminary results of a prospective, randomized study of ACDF versus CerviCore with regards to clinical improvement” CNS, San Diego, September 2007

Floman JE, Gratch MJ, Maroon JC, Hsiang J. “CerviCore Disc Replacement vs. Fusion: Correlation of Patient Employment Status with Clinical Outcomes.” XIV World Congress of Neurological Surgery, Boston, 2008

Floman JE, Baldwin NG, Hsiang J, Webb S, Youssef JA, Rughani A. “Two-year clinical and radiographic follow-up after cervical intervertebral Arthroplasty: Preliminary Data” CNS Annual Meeting, San Francisco, 2010

Hsiang J. “Preservation of the midline structures in one-level lumbar decompression and fusion surgery. Description of a new technique and assessment of efficacy and complication in 40 patients.” oral presentation, American College of Spine Surgery Annual Conference. Las Vegas, 2011

Dawson JM, Konz GJ, Thomson TO, Hsiang JK. “Wound Management by local hypothermia during lumbar spine surgery.” ORS Annual Meeting, San Francisco, 2012


Hsiang J, Wainer BH, Shalaby IA, et al. "Neurotrophic effects of hippocampal target cells on developing septal cholinergic neurons in culture. Neuroscience 21(2): 333-43, 1987.

Hsiang J, Price SD, Heller A, et al. "Ultrastructural evidence for hippocampal target cell-mediated trophic effects on septal cholinergic neurons in reaggregating cell cultures." Neuroscience 26(2): 417-31, 1988.

Hsiang J, Hoffmann PC, Heller A, et al. "The effects of nerve growth factor on the development of septal cholinergic neurons in reaggregate cell cultures." Neuroscience 29(1): 209-23, 1989.

Hsiang J, Chesnut RM, Crisp CB, et al. "Early, routine paralysis for intracranial pressure control in severe head injury: Is it necessary?" Critical Care Medicine 22: 1471-1476, 1994.

Hsiang J, Moorhouse D, and Barba D. "Multiple plasma cell granulomas of the central nervous system. Report of a case." Neurosurgery 35: 744-747, 1994.

Hsiang J, Lam KK, and Poon W. “Patients with chronic intractable pain: Who can benefit from surgical procedures?” Hong Kong Practitioner 17 (6): 1-4, 1995.

Beutler AS, Hsiang J, Moorhouse D, et al. "Pilocytic astrocytoma presenting as an extraaxial tumor in the cerebellopontine angle" Neurosurgery 37: 125-128, 1995.

Lam MK, and Hsiang J. “Minimally invasive neurosurgery: Neuroendoscopy” ELSA 1: 33-34, 1995.

Liang EY, Chan M, Hsiang JHK, et al. “Detection and assessment of intracranial aneurysms: value of CT angiography with shaded-surface display” Am J Radiology 165: 1497-1502, 1995.

Hsiang J, Liang E, Zhu XL et al.: “The role of computed tomographic angiography in the diagnosis of intracranial aneurysms and emergent aneurysm clipping” Neurosurgery 38: 481-487, 1996.

Hsiang J, Cheung T, Goh K et al.: “Features of head injury in Hong Kong (1989-1993)” HKMJ, 2: 141-145, 1996.

Hsiang J, Ng HK, and Poon WS: “Atypical monoclonal plasma cell hyperplasia: its identity and treatment” J of Neurosurgery 85: 697-700, 1996.

Hsiang J, Zhu XL, Wong L et al.: “Putaminal and thalamic hemorrhage in ethnic Chinese living in Hong Kong” Surgical Neurology 46: 441-445, 1996.

Hsiang J. et al.: “Features of pediatric head injury in Hong Kong.” Child Nervous System, 12: 611-614, 1996.

Hsiang J, Ng HK, Tsang KY et al. “Dural Cavernous angiomas can also occur in children.” Pediatric Neurosurgery, 25: 105-108, 1996

Hsiang J, Poon WS “Preventable cause of spontaneous intracranial hemorrhage in Hong Kong Chinese.” HKMJ, 2: 373-376, 1996.

Lam MK, Hsiang J, Poon W: “Monitoring of autoregulation using laser Doppler flowmetry in patients with head injury.” J Neurosurg, 86: 438-445, 1997.

Hsiang J, Yeung T, Yu LM et al. “High-risk mild head Injury” J Neurosurgery, 87: 234-238, 1997.

Hsiang J. et al. “The time course and regional variations of lipid peroxidation after diffuse brain injury in rats.” Acta Neurochirurgica, 139: 464-468, 1997.

Hsiang J, Wong KS, Kay R. et al. “ Vagus nerve stimulation for seizure control: local experience.” J Clinical Neurosci, 5: 294-297, 1998.

Hsiang J, and Poon WS: “Post-concussion syndrome after mild head injury, how significant is that?” J Clinical Neurosci, 5: 399-401, 1998.

Goh KYC, Hsiang JNK, Zhu XL et al. “Intraventricular recombinant tissue plasminogen activator for treatment of spontaneous intraventricular hemorrhage in pregnancy: case report” J of Clin Neurosci, 6: 158-159, 1999.

Ke C, Poon WS, Hsiang JNK et al. “The impact of acute hyponatraemia on severe traumatic brain injury in rats.” Acta Neurochir, 76:405-408, 2000 [suppl].

Kopacz DJ, Helman JD, Nussbaum CE, Hsiang JNK et al. “A comparison of epidural levobupivacaine 0.5% with or without epinephrine for lumbar spine surgery.” Anesth Analg, 93:755-760, 2001.

Hsiang J. “Unconventional indications for using open kyphoplasty.” The Spine Journal, 3:520-523, 2003.

Teng H, Hsiang J et al. “Surgery in the cervicothoracic junction with an anterior low suprasternal approach alone or combined with manubriotomy, sternotomy, and thoracotomy: an approach selection method based on the cervicothoracic angle” Journal of Neurosurgery Spine, 10:531-542, 2009.

Hsiang J. “Five consecutive levels treated with Cortoss bone augmentation material.” Orthovita. White paper. 2010

Hsiang J, “Wrong-level surgery: A unique problem in spine surgery.” Surgical Neurology International, 2:47, 2011

Hsiang J, “Minimally invasive one-level lumbar decompression and fusion surgery with posterior instrumentation using a combination of pedicle screw fixation and transpedicular facet screw construct.” The Spine Journal, submitted.


Lecture: "Management of Neurosurgical Patients." Nurse Review Course, San Diego VA Hospital. January 19, 1993.

Honorary Clinical Lecturer in Neurosurgery: Prince of Wales Hospital/The Chinese University of Hong Kong: Hong Kong. February, 1993.

Paper Oral Presentation: "Early, Routine Paralysis for ICP Control in Severe Head Injury: Is It Necessary?" 2nd International Neurotrauma Symposium. Glasgow, Scotland. July 4-9, 1993.

Lecture: "ICP Management in Severe Head Injury Patients." Surgical ICU nurses, UC San Diego Medical Center. September 23, 1993.

"Management of Spinal Cord Injury." Surgical ICU, UC San Diego Medical Center. October 21, 1993.

Lecture: "Barbiturate Coma for ICP control." Surgical ICU, UC San Diego Medical Center. November 18, 1993.

Speaker: "Free Radicals and CNS Injury." Cheju Neurosurgery Friendship Conference. Cheju, Korea. December 2-6, 1993.

Lecture: "New treatments in Head Injury." General Surgical residents, UC San Diego Medical Center. January 13, 1994.

Lecture: “Epilepsy Surgery” Surgical Grand Round, Prince of Wales Hospital. November, 1994.

Discussant: “New trend of pathophysiology of head injury” Head injury Round Table Discussion at the 9th Asian-Australasian Congress of Neurological Surgery. November, 1995.

Speaker: “Vagus Nerve Stimulation for Intractable Epilepsy Control” Plenary session at the First Asian Epilepsy Symposium. April, 1996.

Speaker: “New Trend in Severe Head Injury Management” at Hunan Medical University, April, 1996

Speaker: “What’s New about Neurosurgery Nowadays” at Hunan Medical University, April, 1996.

Speaker: Grand Round, “ Kyphoplasty, new treatment of osteoporotic vertebral compression fracture” Virginia Mason Medical Center, February, 2002.

Honorary Visiting Scholar in Neurosurgery: Sir Run Sun Shaw Hospital (associated with Loma Linda Hospital), Hangzhou, China. June 2002.

Speaker: Low Back Pain Care for the Primary Care Provider. Virginia Mason Medical Center, April, 2003.

Instructor: Spine Operating Room Personnel Course, by AO North America. Seattle, July 2003

Speaker: Normal Pressure Hydrocephalus. In The 1st Academic Conference of International Chinese Neurosurgical Sciences. Boao Hainan, China, March 2004.

Podium Presentation: Cervicore Disc Replacement vs. Fusion for Cervical Radiculopathy: One-Year Outcomes from Four Sites in a Prospective Randomized Controlled Trial. The 15th International Meeting on Advanced Spine Techniques. Hong Kong . July 9th 2008

Faculty: Cervical Spine Surgery Course, The Chinese University of Hong Kong. April 2004

Faculty: The Future of Spine Surgery. In Pain Symposium, Swedish Medical Center. September 30, 2005

Faculty: Treating Complex Spinal Pathologies. Monterey, California. November, 2006

Faculty: Advanced Techniques in Minimally Invasive Surgery. Seattle, Washington. July 25, 2008

Consultant: Minimally Invasive Spine Surgery, Motion preservation, Stryker Spine

Consultant: Retractor for Minimally Invasive Spine Surgery, Zimmer Spine

Speaker: Innovation is Spine Surgery. Washington State Nursing Symposium. February 27, 2009

Co-Chairman: A New Paradigm in Treating and Preventing Disability in Low Back Pain Patients. Swedish Neuroscience Institute Symposium. April 3, 2009

Speaker: “The Differences in Spine Surgery Between China and the US” General Hospital of Air Force, Beijing, China. January 26, 2010

Guest Professor: The Department of Orthopedic Surgery, General Hospital of Air Force, China

Speaker: “Preservation of the Midline Structures During Multilevel Lumbar Decompression and Fusion – Revisit of the Wiltse Approach” Zhongshan Hospital, Shanghai, China. January 28, 2010

Faculty: “Advances in Total Spondylectomy and New Technology in Spine Surgery” Zhongshan Hospital, Shanghai, China. May 7-9th, 2010

Speaker: “Wrong Level Surgery: A Unique Problem in Spine Surgery” Washington State Association of Neurological Surgeons Annual Meeting. May 22nd, 2010

Faculty: “Management of Hospitalized Neurological and Neurosurgical Patients.” Swedish Medical Center. June 11, 2010

Co-Chairman: “How Comfortable Are You Treating Spine Patients?” Swedish Medical Center Symposium. June 25, 2010

Faculty: “Spine Emergency and Management of Patients with Spine Surgery” American Society of Perianesthesia Nurse 30th National Conference. April 5, 2011

Faculty: “Strategic Management of Healthcare Organization” for hospital management courses provided by Executive Education and International Initiatives, Foster School of Business, University of Washington, 2012

Speaker: “Minimally invasive one-level lumbar decompression and fusion surgery with posterior instrumentation using a combination of pedicle screw fixation and transpedicular facet screw construct.” Sichuan-Chongqing Orthopedic Conference, July 27, 2012


Creating the future through research at SNI

September 03, 2010

Clinical research is an essential component of Swedish Neuroscience Institute (SNI). It provides our patients therapeutic options that would otherwise be unavailable to them and places our staff at the forefront of medical knowledge as they evaluate leading-edge drugs and medical devices. The majority of SNI investigations assess the safety and efficacy of new drugs and devices. These studies are typically sponsored by the federal government, or pharmaceutical and medical device companies, with oversight provided by the U.S. Food and Drug Administration. Investigator-initiated trials at SNI answer questions about current standard-of-care therapies. These trials play an important role in supporting evidence-based medicine and advancing patient care.

Initiating a research study at SNI begin...

Comprehensive Spine Center at SNI

August 27, 2010

Neck pain and low back pain are common health problems in the US. They are among the top reasons for doctor visits. They are also the number one cause of disability for people under 45 years of age in the US. The Comprehensive Spine Center at SNI consists of spine surgeons, physiatrists, interventional pain specialists, neuroradiologists, and physical therapists. All these spine specialists can provide the best and most advanced spine care to our patients in the same clinic. We strive to make spine care as convenient as possible to our patients.

The spine center at SNI provides a wide spectrum of surgical procedures to treat spine disorders caused by degeneration, neoplasm, infection, congenital malformation, and trauma. We distinguish ourselves not only by providing superb care to our patients, but also driving new technologies in spine surgery. SNI is the leading center in large clinical trials for cervical artificial disc im...

Clinical Experience

  • Neurological Surgery
  • Spine Surgery
Clinical Interests
  • Back/Spine Injuries
  • Back/Spine Surgery
  • Cervical Injury/Problems
  • Cervical Spine Problems/Proc.
  • Cervical/Lumbar Degen. Disorders
  • Disc Problems
  • Disc Replacement
  • Endoscopic Surgery
  • Minimally Invasive Spine Surgery
  • Minimally Invasive Surgery
  • Neurosurgery
  • Nucleoplasty
  • Schwannoma
  • Sciatica
  • Spinal Cord Injury
  • Spinal Disorders
  • Spine Surgery
  • Spine Tumor/AVM Embolization
  • Vertebroplasty


Patient Ratings and Comments

The Patient Rating score is based on responses given during the CAHPS Patient Experience Survey. Responses are measured on a 10-point scale, with 10 being the best score. These scores are then translated to a 5-point scale in order to display results in a 5-star rating. Comments are also gathered from the same survey and displayed in their entirety with the exception of any language that may be considered slander, libel or contain private health information, which will be removed prior to publishing the comments.

4.1 out of 5 (34 Ratings, 8 Comments)


Terrible brought 4 assistants.

[...] this is my third surgery scheduled to be performed by Dr. Hsiang and his Staff. I really appreciate the concern and care provided by Dr. Hsiang and his Staff--very organized and helpful making sure that the patient doesn't have any concerns about arranging tests needed.

BAD experience as provider was rushed due to examination being interrupted by "patient is prone and waiting in surgery" and, therefore, his leaving after approx. 10 minutes for this more urgent situation The office visit was useless to me and a waste of time and money. Provider will not see me in his operating room.

Very intelligent confident. Excellent provider.

Dr. Hsiang was highly recommended by a friend who is a surgical nurse, and lived up to his reputation. I have absolute confidence in the man. I actually enjoyed the time I spent with the rest of my team. I was tired after a long drive from Port Angeles, and in pain, but they lifted my spirits. It felt like talking with friends. A+ for them!

Awesome dr., staff & hospital.

Dr. Hsiang is a fine surgeon. His ego is too big to listen to real concerns and adjust to those concerns and address them.PA [...] is his saving grace as far as "bedside manner"

This provider ordered exactly the right tests for me that revealed important problems. I am grateful for that. He also made an excellent referral for me, that looks like it will have a very good outcome.
751 NE Blakely Drive
4th Floor
Issaquah, WA 98029
751 NE Blakely Drive
Suite 4020, 4th Floor
Issaquah, WA 98209
(425) 313-7180
Affiliated Facilities