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A phase 3, multicenter study designed to evaluate the efficacy and safety of a long-acting hGH product (MOD-4023) in adult subjects with growth hormone deficiency

Growth Hormone Deficiency (GHD) is caused by the insufficient secretion of naturally produced human growth hormone (hGH).  MOD-4023 has the same...

Zachary N. Litvack, MD MCR FAANS

A feasibility study to evaluate safety and initial effectiveness of Exablate Transcranial MR Guided Focused Ultrasound for Unilateral Thalamotomy in the treatment of Medication-Refractory Tremor Dominant Idiopathic Parkinson's Disease.

To test the safety and initial efficacy of treatment using the ExAblate Transcranial System against a sham control in medication-refractory tremor...

Ryder Gwinn, MD

A Study to Evaluate the Safety and Feasibility of Transcranial MRI-Guided Focused Ultrasound Surgery in the Treatment of Brain Tumors.

The purpose of this study it to evaluate the safety of MRI-guided focused ultrasound thermal ablation of brain tumors performed through intact...

Stephen Monteith, MD

A randomized, double-blind, placebo-controlled, multi-center trial to evaluate the safety and efficacy of Eculizumab in patients with relapsing neuromyelitis optica (NMO)

This study is to assess the efficacy and safety of eculizumab treatment as compared to placebo in relapsing NMO patients using a time to first...

Pavle Repovic, MD

A Randomized Phase 3 Open Label Study of Nivolumab Versus Bevacizumab and Multiple Phase 1 Safety Cohorts of Nivolumab or Nivolumab in Combination With Ipilimumab Across Different Lines of Glioblastoma

The purpose of the study is to compare the efficacy and safety of nivolumab administered alone versus bevacizumab in patients diagnosed with...

Tara L. Benkers, MD

Phase 2 Dose-Escalation Study of TPI 287 in Combination With Bevacizumab in Adults With Recurrent or Progressive Glioblastoma Following a Bevacizumab-Containing Regimen

The purpose of this study is to evaluate the safety, maximum tolerated dose (MTD), and efficacy of TPI 287 in combination with Avastin...

Tara L Benkers, MD

A phase IIIb double-blind multicenter study to evaluate the efficacy and safety of Alteplase in patients with mild stroke: rapidly improving symptoms and minor neurologic deficits (PRISMS)

The primary objective of this study is to determine the efficacy of intravenous (IV) alteplase for treatment of acute ischemic stroke (AIS) in...

Aaron Stayman, MD

Phase 1/2 Dose-Escalation Study of TPI 287 in Combination With Bevacizumab Followed by Randomized Study of the Maximum Tolerated Dose of TPI 287 in Combination With Bevacizumab Versus Bevacizumab Alone in Adults With Recurrent Glioblastoma

This trial is divided into two parts, a dose-escalation study (phase 1) and a randomized study (phase 2). The purpose of the dose-escalation study...

Tara Benkers, MD

Gamma Knife Thalamotomy for Treatment of Essential Tremor

The purpose of this study is to find out what effects (good and bad) gamma knife radiosurgery has on essential tremor.  STUDY OBJECTIVES: ...

Christopher Loiselle, M.D.
Radiosurgery Center

A Phase 4 Multicenter, Open-Label, Single Arm study to evaluate switching from BRACET/Gilenya to Natalizumab in subjects with relapsing forms of Multiple Sclerosis(MS).

The purpose of this study is to assess the proportion of subjects who attain no evidence of disease activity (NEDA) on Tysabri (natalizumab) after...

Pavle Repovic, MD, PhD
Viewing Page 2 of 4 | Showing Results 11 - 20 of 35