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A Double-Blinded, Placebo-Controlled, Randomized Phase II Study of Enzalutamide With or Without the PI3 Kinase/mTOR Inhibitor LY3023414 in Men With Metastatic Castration Resistant Prostate Cancer

The main purpose of this study is to evaluate the safety and effectiveness of the study drug known as LY3023414 in combination with enzalutamide in...

Song Zhao, MD, PhD
Swedish Cancer Institute

A Phase 1b Open-Label Study of PEGylated Recombinant Human Hyaluronidase (PEGPH20) Combined with Pembrolizumab in Subjects with Selected Hyaluronan-High Solid Tumors

This is a phase 1b study evaluating a combination of PEGPH20 and pembrolizumab for subjects with relapsed/refractory advanced or metastatic Non...

Philip Gold, MD
Swedish Cancer Institute

A Phase 3, Multicenter, Randomized, Open-label Study to Compare the Efficacy and Safety of Pomalidomide (POM), Bortezomib (BTZ) and Low-Dose Dexamethasone (LD-DEX) Versus Bortezomib and Low-Dose Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma

Purpose The purpose of this study is to compare the efficacy of the combination of Pomalidomide, Bortezomib and Dexamethasone to the combination...

Michael S. Milder, MD
Swedish Cancer Institute

REPRISE III: REPOSITIONABLE PERCUTANEOUS REPLACEMENT OF STENOTIC AORTIC VALVE THROUGH IMPLANTATION OF LOTUS VALVE SYSTEM - RANDOMIZED CLINICAL TRIAL EVALUATION

To evaluate the safety and effectiveness of the Lotus Valve System for transcatheter aortic valve replacement (TAVR) in symptomatic subjects with...

Robert Bersin, MD

LIFE Study: Least Invasive Fast-Track EVAR With the Ovation Prime™

The LIFE Study is a prospective, non-randomized multi-center post-market registry to evaluate the Ovation Prime Abdominal Stent Graft System when...

Robert Bersin, MD

The Prospective Randomized On-X Valve Anticoagulation Clinical Trial (PROACT)

A longitudinal, randomized study comparing the On-X valve on low dose anticoagulation (test group) to concomitant control groups of On-X valves...

Glenn Barnhart, MD

A Phase 1b Study of SAR650984 (Isatuximab) in Combination With Pomalidomide and Dexamethasone for the Treatment of Relapsed/Refractory Multiple Myeloma

Primary Objective: Safety Secondary Objective: Efficacy, Pharmacokinetics (PK)

William Bensinger, MD
Swedish Cancer Institute

Connect® MDS/AML: The Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) Disease Registry

The purpose of the Connect® MDS/AML Disease Registry is to provide unique insights into treatment regimens and sequencing of these regimens as...

Henry Kaplan, MD
Swedish Cancer Institute
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