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A Phase 1b/2 Study of OMP-59R5 in Combination With Etoposide and Platinum Therapy in Subjects With Untreated Extensive Stage Small Cell Lung Cancer (PINNACLE)

The study consists of a Phase1b lead-in portion to determine the MTD of OMP-59R5 in combination with EP for 6 cycles followed a Phase 2,...

Howard West, MD
Swedish Cancer Institute

A Phase 1b Open-Label Study of PEGylated Recombinant Human Hyaluronidase (PEGPH20) Combined with Pembrolizumab in Subjects with Selected Hyaluronan-High Solid Tumors

This is a phase 1b study evaluating a combination of PEGPH20 and pembrolizumab for subjects with relapsed/refractory advanced or metastatic Non...

Philip Gold, MD
Swedish Cancer Institute

USPELLA (IMPELLA 2.5®) DATA REGISTRY

The USpella data registry is collecting and analyzing existing patient records to develop best practice guidelines for the patients requiring...

John L. Petersen II, MD

The CALIBER Study Randomized Controlled Trial of LINX Versus Double-Dose Proton Pump Inhibitor Therapy for Reflux Disease

This study compares mechanical sphincter augmentation (LINX Reflux Management System) to double-dose proton pump inhibitors (PPIs) for the...

Brian Louie, MD
Swedish Cancer Institute

ENDOVASCULAR INTERVENTIONS WITH ANGIOMAX: THE ENDOMAX TRIAL

The main purpose of this study is to compare the effects of bivalirudin in reducing blood clots when compared to unfractionated heparin; which is...

Robert Bersin, MD

NMARQ PULMONARY VEIN ISOLATION SYSTEM FOR THE TREATMENT OF PAROXYSMAL ATRIAL FIBRILLATION

This study compares the safety & effectiveness of the nMARQ Pulmonary Vein Isolation System to the FDA-approved Thermocool Navigational group...

Darryl Wells, MD

A MULTICENTER RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED PHASE IIIB STUDY TO EVALUATE THE EFFICACY SAFETY AND TOLERABILITY OF SERELAXIN WHEN ADDED TO STANDARD THERAPY IN ACUTE HEART FAILURE PATIENTS (RELAX AHF)

This study is sponsored by the pharmaceutical company named Novartis. If you agree to join the study you will receive either serelaxin or placebo...

John L. Petersen II, MD

The Prospective Randomized On-X Valve Anticoagulation Clinical Trial (PROACT)

A longitudinal, randomized study comparing the On-X valve on low dose anticoagulation (test group) to concomitant control groups of On-X valves...

Glenn Barnhart, MD
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