5447W-13: Pfizer A3921119

Dose-Ranging Study Of Tofacitinib In Adults With Active Ankylosing Spondylitis

Type of Study
Rheumatology - Ankylosing Spondylitis
Short Description

This is the first study of oral tofacitinib in adults with active ankylosing spondylitis. It is designed to obtain information on the efficacy and safety of 3 different doses of tofacitinib.


Status
Open
Principal Investigator
Philip J. Mease, MD
Eligibility Notes

Inclusion Criteria:

  • Documented diagnosis of Ankylosing Spondylitis
  • Has active disease despite concurrent nonsteroidal anti-inflammatory drugs (NSAIDs) treatment or is intolerant to NSAIDs

Exclusion Criteria:

  • Pregnant or lactating females
  • Currently receiving or previous use of a Tumor Necrosis Factor (TNF) inhibitor or any biological agent
Start Date
9/10/2013
Contact Name
Allison Everett
Phone
206-386-3201
Alternate Phone
206-386-6248
Email
Allison.Everett@swedish.org
Alternate Email
Sephren.Barrow@swedish.org