Intravenous acetaminophen for craniotomy patients
Explore if using intravenous acetaminophen just before and just after a craniotomy can reduce the amount of opioids a patient needs, which results in less nausea and vomiting.
Neuroscience - Craniotomy /Interventional,
Arthur M. Lam, M.D.
- Male or female patients 18 years of age or older.
- Undergoing an open, elective intracranial procedure for tumor resection aneurysm clipping, or revascularization.
- Have an ASA (American Society of Anesthesiologists) status of 1, 2, 3, or 4.
- Have a condition or disease that, in the opinion of the Principal Investigator, would compromise the patient's welfare or safety
- Current daily chronic opioid use in excess of 40-mg morphine equivalents or any tramadol use.
- Treated with MAO inhibitors 10 days before surgery.
- Treated with any amount of acetaminophen within 8 hours of anesthesia.
- Have known hypersensitivity to acetaminophen or the inactive ingredients of IV acetaminophen or anycontraindication per manufacturer's guidelines.
- Impaired liver function.
- Participation in an interventional clinical study w...