Intravenous acetaminophen for craniotomy patients
- Type of Study
- Neuroscience - Craniotomy /Interventional
- Short Description
Explore if using intravenous acetaminophen just before and just after a craniotomy can reduce the amount of opioids a patient needs, which results in less nausea and vomiting.
- Principal Investigator
- Arthur M. Lam, M.D.
- Eligibility Notes
- Male or female patients 18 years of age or older.
- Undergoing an open, elective intracranial procedure for tumor resection aneurysm clipping, or revascularization.
- Have an ASA (American Society of Anesthesiologists) status of 1, 2, 3, or 4.
- Have a condition or disease that, in the opinion of the Principal Investigator, would compromise the patient's welfare or safety
- Current daily chronic opioid use in excess of 40-mg morphine equivalents or any tramadol use.
- Treated with MAO inhibitors 10 days before surgery.
- Treated with any amount of acetaminophen within 8 hours of anesthesia.
- Have known hypersensitivity to acetaminophen or the inactive ingredients of IV acetaminophen or anycontraindication per manufacturer's guidelines.
- Impaired liver function.
- Participation in an interventional clinical study within 30 days of enrollment.
- Known or suspected history of drug or alcohol abuse.
- Surgery for resection of acoustic neuroma.
- Surgery using a transphenoidal approach for tumor resection.
- Contact Name
- Becky Wood
- Alternate Phone