Swedish News Blog

Exciting Advances in Multiple Sclerosis from ECTRIMS

Karen Pabillon

There is exciting news from last week’s 26th Congress of the European Committee for the Treatment and Research in Multiple Sclerosis (ECTRIMS) in Gothenburg, Sweden.

ALEMTUZUMAB. 5-year data from a Phase II extension study for alemtuzumab, an intravenously administered monoclonal antibody, showed that the drug:

  • reduced annualized rate of relapse to 0.14 compared with 0.28 for interferon
  • reduced the risk for sustained accumulation of disability in remitting relapsing multiple sclerosis by 87% compared to 62% with interferon.

This is a remarkable agent with excellent activity in MS. Adverse events included immune thrombocytopenic purpura, thyroiditis and anti-glomerular basement membrane disease.

TERIFLUNOMIDE. A Phase III trial of oral teriflunomide in remitting relapsing MS showed:

  • a 31% reduction in relapse rate and increased time to first relapse compared with placebo
  • reduced the risk of sustained disability progression by 29.8%.

Side effects were mild and included diarrhea, nausea, liver function abnormalities and hair loss.

Alemtuzumab and teriflunomide are currently in Phase III clinical trials at SNI.

SNI PRESENTATIONS:

  • Dr. Jim Bowen presented a poster about ongoing demyelination and neurodegeneration in a patient who had undergone autologous stem cell transplantation.
  • Drs. Jung Henson and Mayadev reviewed the beneficial effects of exercise on functional and quality of life outcomes from SNI’s MS wellness program

Swedish Smyelin Babes Kick Into High Gear

John W Henson IV

John W Henson IV
Director, Neurology

 
The Bike MS Ride in Mount Vernon is almost here (September 11-12) and the Swedish Smyelin Babes bike team is 98 members strong and still growing! The team started out with 4 riders in 2006, and since then has grown to be the largest bike team, beating out even corporate groups like Team BP, Microsoft, Columbia Athletic Club and Point B. We are also the only bike team representing any of the MS centers in the Seattle region. Last year we raised over $84,000 to support the National Multiple Sclerosis Society, and we hope to beat that amount this year. Join Swedish Smyelin Babes or donate to this worthy cause!
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