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Human Papillomavirus (HPV) in Head and Neck Cancer

Cancer of the oropharynx (throat) has undergone a drastic and dramatic change over the last decade.  In the past, most throat cancers were linked with prolonged cigarette smoking and alcohol use.  Now, the occurrence of throat cancer is rising and 80-90% is likely caused by an infection with Human Papillomavirus (HPV).  Many high-profile personalities, including actor Michael Douglas and JP Morgan CEO Jamie Dimon, have recently revealed that they have experienced HPV-related throat cancer.

What causes HPV-related Oropharynx cancer?

Infection with the Human Papillomavirus (HPV) is known to cause genital warts and lead to various genital cancers, but now it appears to also cause the majority of throat cancers.  The types of HPV that lead to throat cancer are generally sexually transmitted, though some researchers believe that even kissing may result in HPV transmission.   The time period from HPV exposure to the development of a throat cancer is often decades. Although the cancer may be slow-growing, it is important to have annual check-ups with your physician and dentist who can assess your oral health appropriately. 
 
How is HPV-related Oropharynx cancer treated?


HPV-related throat cancer can ...

Mesothelioma update: shorter course of treatment and improved survival rates?

There have been some very exciting recent developments we (the Thoracic Surgery team at Swedish Cancer Institute) are utilizing in the treatment of malignant pleural mesothelioma (MPM).

Over the past year we have offered some of our patients deemed appropriate for surgery a more streamlined approach to their overall care. Previously we have tried to offer chemotherapy, surgery, and radiation to all patients who were healthy and strong enough to undergo the three treatments, as mesothelioma is an aggressive cancer requiring aggressive treatment to optimize survival. This new approach still offers both surgery and radiation, but chemotherapy is given only to those found to have cancer in lymph nodes in the center of chest during surgery.

The advantages of this new treatment paradigm are ...

Dealing with vaginal dryness

One of the more annoying situations that many of my patients have been in is having painful intercourse due to vaginal dryness. In general the cause of dryness of the vaginal tissue is lack of estrogen. This can occur postpartum, especially in women who are breastfeeding a baby, and it can occur just before and during menopause.

When estrogen is in the body, one of the effects of estrogen is to ...

Reducing visits to the operating room for breast cancer patients

Swedish Cancer Institute has changed the way early stage breast cancer patients are cared for by adopting new surgical margin guidelines.  These guidelines will reduce the need for taking women back to the operating room if cancer cells are found at or near the specimen edge, also known as the margin. Following extensive review of the data, this new guideline was established by breast experts from the Society of Surgical Oncology and the American Society of Radiation Oncology and has been endorsed by the American Society of Breast Surgeons and the American Society of Clinical Oncology.
 
Many women with early stage invasive breast cancer opt for breast conserving surgery, known as lumpectomy or partial mastectomy. For 20-25% of these patients, a second surgery or re-excision was performed because the margin was not considered adequate based on previous practice guidelines. The latest peer reviewed evidence shows disease control is excellent when surgery is combined with whole breast radiation with or without hormonal therapy and/or chemotherapy, regardless of the margin width.
 
The Swedish Cancer Institute’s multidisciplinary breast cancer team reviewed and approved these guidelines for our program. We believe by reducing the need ...

New products available for allergy treatment

For those with seasonal allergies, treatment can be as simple as an over-the-counter medication, but often requires more.  The good news is that there are a lot of options now. Some new products have been recently approved by the FDA to help individuals who are dealing with grass and ragweed allergies.

The treatment of nasal and eye symptoms from allergies includes antihistamines, nasal sprays and allergy shots.  Over the counter antihistamines include diphenhydramine (ex. Benadryl), loratadine (ex. Claritin), cetirizine (ex. Zyrtec), or fexofenadine (ex. Allegra).  Over the counter allergy eye drops are also available, such as ketotifen (ex.Zaditor).  Together, these help with itchy, sneezy, watery nose and eyes.  Nasal antihistamines are prescription and also help with these symptoms.  Nasal steroids help decrease congestion and postnasal drip.  

A long-standing solution ...

Facts and myths about antioxidants and cancer

Some of the most popular misconceptions surrounding cancer, cancer prevention and cancer treatment are about the role of antioxidants. Like many of the popular myths about cancer, there are facts, half-facts and outright falsehoods.
 
Fact: Damage to genes, particularly those involved in the regulation of cell division and cell death, is the key event in the development of cancer. 
Fact: Oxidants are substances, most often generated by our own body, that cause damage to chemicals, including the DNA that makes up our genes, by oxidizing them. The oxidation reaction most familiar to us is when metal rusts. 
Fact: Our bodies’ oxidants can contribute to cancer.
 
Half-fact: Antioxidants are chemicals we ingest that then run around neutralizing oxidants, rendering them powerless to promote cancer. The so-called antioxidant vitamins, of which vitamin C, E, and beta-carotene are the most well known are more properly called redox agents. In a particular environment, they prevent or reverse oxidation, called reduction. But they may change the acidity or even just the concentrations of the components of the reaction, and they may facilitate just the opposite. For example ....

Why aren't my bowel habits normal?

Do you have irregular, uncomfortable, or distressing bowel habits? Irritable Bowel Syndrome (IBS) is the most common gastrointestinal condition affecting an estimated 15% of the general population.  It is most common among women aged 30 to 49 years old.

IBS is a chronic condition of the digestive system that is not generally associated with more concerning findings of anemia, weight loss, family history of colorectal cancer, inflammatory bowel disease, or celiac disease. Symptoms of IBS include abdominal discomfort, constipation and diarrhea. Despite extensive research, no common cause of IBS has been identified. Some theories include:
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