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'multiple sclerosis' posts

MS in the Pacific Northwest on 12/9

All are invited to attend the presentation, “Multiple Sclerosis in the Pacific Northwest,” on Monday, Dec. 9 at 7 p.m. in Kirkland. I'll discuss multiple sclerosis as a disease, trends, changes in its distribution around the world, and how it uniquely impacts our region. The presentation is free and is open to all ages. Click here for more information.

2013 World Atlas of MS published

The 2013 World Atlas of MS has been published by MS International Foundation and is available here. The key findings are:

  1. The estimated number of people with MS has increased from 2.1 million in 2008 to 2.3 million in 2013
  2. The 2:1 ratio of women to men with MS has not changed significantly since 2008
  3. Substantial global inequalities remain in terms of access to treatment and medical care

Constraint induced movement therapy in MS may be equally effective as in stroke

Constraint induced movement therapy (CIMT), formerly called “forced use” is a treatment for impaired function of an upper extremity. It has been established as an effective evidence-based form of treatment for rehab of impaired upper extremity (UE) function for post stroke hemiparesis. The core features of CIMT are massed practice (high repetitions) and to overcome learned non-use thru behavior modification. The typical training protocol involves a 2 week period of physical restraint of the less-involved side (90% of the waking hours) and intensive training (3 hours/day) focused on movement patterns of the involved hand and arm. The physical restraint is usually a padded mitt, sling or glove thereby restricting stronger arm use.
At a recent ECTRIMS/RIMS meeting, this form of therapy was presented as being equally effective in

Research and progress for progressive Multiple Sclerosis (MS)

I am delighted to write the blog over the Progressive MS session that was given at ECTRIMS 2013.  Much emphasis has been given to the need for more research in the fields of progressive MS.  The majority of MS patients fit into this broad category: primary progressive MS, secondary progressive MS, and progressive relapsing forms of the disease.  During a session devoted to progressive MS, leaders in the field discussed several initiatives underway to address the challenges presented by these forms of the disease. 

Rehabilitation is a mainstay and key to improving the lives of patients with progressive MS. Many patients describe their progression in terms of mobility decline, which is a major target of improvement in rehabilitation programs.

The first session was devoted to confusion surrounding the definition of “progression in MS.”  We use ...

Service animals help support people with MS

On October 21, 2013 the Multiple Sclerosis Center at Swedish Neuroscience Institute hosted a meet and greet with Buddy Hayes, national speaker for Canine Companions for Independence.  Buddy, as she prefers to be called, is a military veteran and the owner of Stanford, a handsome Labrador Retriever service dog given to her by Canine Companions for Independence.

Canine Companions for Independence is the largest national nonprofit organization provider of assistance dogs in the United States.  Canine Companions proudly provides assistance dogs to people in need completely free of charge.  They use hundreds of volunteers around the country and an expert team of professionals to deliver a service that allows people to continue living active and independent lives with the help of a professionally trained dog.

Stanford has been taught to make Buddy’s life easier and safer.  For example, Stanford can help open doors, turn lights on/off, pick up dropped items, and pull her lightweight wheelchair if needed.  One of the very practical lessons a dog is taught is to go to the bathroom on verbal command.  To obtain a service dog, one must ...

Testosterone is associated with worse disease severity in men with early relapsing onset multiple sclerosis

MS and many other autoimmune diseases are less common in men than in women. This is especially true during reproductive years. Sex hormones, including testosterone and estrogen, may be responsible for the difference. It is thought that men with multiple sclerosis may have lower testosterone levels than healthy controls.

Dr. Bove and his group assessed the prevalence and clinical associations of hypogonadism in men with recent onset relapsing multiple sclerosis.  Male subjects from the Comprehensive Longitudinal Investigations of MS at the Brigham and Women's Hospital (CLIMB) cohort were included. Hormonal measures included testosterone, the testosterone: estradiol ratio, leutinizing hormone (LH), and free testosterone. Clinical outcomes were collected every 6 months for Expanded Disease Severity Scale (EDSS), and annually for Symbol Digit Modalities test (SDMT).

The analysis included 96 men with a mean age of 40 years, disease duration of 4.6 years; 71% subjects were untreated at baseline. Of these men, 39% were ...

Gut Microbiome: Studying the links between people, bacteria, and MS

Our bodies are made of billions of cells. However, the cells in our bodies are far outnumbered by the bacteria that cover our skin and inhabit our gut. These bacteria are now increasingly recognized to have an important role in maintaining our health. For example, skin bacteria help protect us from more dangerous bacteria that could invade us. Gut bacteria help digest our food. There are suggestions that changes in these bacteria, particularly those in the gut, might play a role in several diseases.

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