Tags
Swedish Multiple Sclerosis Blog Blog

'MS Center' Swedish Multiple Sclerosis Blog posts

Statin Benefits Secondary Progressive MS

No treatments can currently abate the advanced stage of the disease, known as secondary progressive MS, which gradually causes patients to become more disabled. Statins are postulated to have immunomodulatory effects that appear to be independent of their effect on cholesterol. A benefit has been suggested in early multiple sclerosis (MS) based on reduction of magnetic resonance imaging brain lesions.  However, following trials have had inconsistent results.

In this multicenter, double-blind study, investigators randomized 140 participants with secondary progressive (SP) MS to 80 mg of simvastatin or placebo daily for 2 years. Participants were 18 to 65 years old, had active progression over the preceding 2 years, and had difficulties ambulating but were not wheelchair bound.  Whole brain atrophy was 43% slower annually in simvastatin recipients than in placebo recipients. The simvastatin group also had small clinical improvements over placebo on the disability scale and a patient-reported MS impact scale at 24 months.
 
These findings show that simvastatin reduced ...

Importance of planning pregnancies with Multiple Sclerosis (MS)

A recent study addressed the outcomes of pregnancy in women with MS who were taking fingolimod (Gilenya). Of 66 pregnancies on the medication, 41 attempted to carry the pregnancy to term. 26 of the 41 had healthy newborns. There were, 9 miscarriages, 24 elective abortion, 4 ongoing pregnancies and 1 with an unknown outcome. Of the elective abortions, four were for fetal malformations. There were 5 cases with abnormal fetal development in the 66 pregnancies. Poor fetal outcomes were found in 14.6% of the pregnancies. This contrasts with a 3% rate of poor outcomes for most pregnancies.

This paper highlights the importance of care in planning pregnancies in MS. It is now known that women with MS have ...

Special team of volunteers at Swedish MS Center

 
On Thursday, April 10, 2014, Swedish hosted a Volunteer Appreciation Celebration dinner and awards ceremony at the Seattle Tennis Club.  The event was to acknowledge and give thanks to all the volunteers who generously donate their time, and energy, to making Swedish a people friendly place.  The event was attended by more than 220 Swedish volunteers.
 
Our very own Swedish MS Center registered nurse Kim Lozano, and Certified Pet Therapy Volunteer Kathy Knox, and her Certified Therapy Dog Ocho (yellow Labrador retriever) were honored as Swedish’s “Featured Volunteer Program: The Leo Project.”  Kim created The Leo Project, better known as the Leo Pet Therapy Program to enhance the services we offer our MS Center patients and their families.  The name “Leo” was selected to pay tribute to Kim’s beloved dog Leo who passed away at the age of 13. 
 
Kathy Knox and therapy dog Ocho deliver comfort and care to all people who pass through our MS Center’s walls.  Ocho ...

Insufficient evidence to support complementary and alternative therapies for multiple sclerosis

A guideline was recently published about the use of complementary and alternative medicine in multiple sclerosis (MS).

The guideline process involves identifying all of the scientific articles about potential therapies and evaluating them based on their scientific merits. The evaluation process follows a strict set of requirements related to the conduct of the research.

The review included a wide variety of complementary and alternative therapies that have been proposed for MS. Not surprisingly, most therapies did not have sufficient scientific data to determine whether or not they were effective. Some cannabinoid preparations (marijuana extracts) were shown to be effective, primarily for spasticity. This reflects a relatively large number of studies done with these compounds and the availability of a commercially available extract in some countries. A handful of therapies were shown to be ineffective. Most therapies had insufficient studies to determine their effectiveness.

The importance of this review is that it ...

National Stress Awareness Month-Managing stress with multiple sclerosis

April is National Stress Awareness Month so it seems appropriate to look at the impact of stress on people living with MS and to become more aware of what one can do to better manage one’s reaction to the inevitable stressors in life.
 
There is a growing body of research that suggests there is an association between stress and an increased risk of MS exacerbations and the development of new lesions in patients with MS.  A group of Dutch researchers followed 73 patients with RRMS and found that those patients who reported a major stressful event were 2.2 times more likely to have an MS exacerbation in the following four weeks.  In 2006, a group of U.S. researchers followed 36 people with MS and found that after experiencing a major life stress, those MS patients were 1.6 times more likely to develop a new lesion in the next eight weeks.2  The same group of researchers reported that the MS patients with good coping strategies could reduce this risk.
 
The exact mechanism by which stress increases the risk of MS exacerbations and the development of new brain lesions is not entirely clear, but what is known is that stress affects the body’s ability to regulate the inflammatory response, and in patients with MS and other autoimmune disorders, inflammation occurs when  ...

Personal grants for people with multiple sclerosis

Personal grants are available from a variety of MS organizations and offer assistance for everything from mobility equipment to financial support. With summertime fast approaching, grants for cooling equipment for those that are heat sensitive are also available. Check out the links below to learn more about these opportunities.

Functional Electrical Stimulation (FES) braces improve gait

Up to 80 percent of people with multiple sclerosis (MS) have problems with walking.  The combination of weakness of the muscles of the legs, spasticity, and core weakness contributes to this.  Often, it will present with problems lifting the foot, referred to as foot drop.  This is due to weakness of the muscles that lift the foot (dorsiflexors) and spasticity or over power of the muscles that push the foot down (plantar flexors).  Traditional ankle foot orthosis have advantages over functional electrical stimulation (FES) braces in that they help with ankle stability and reduce spasticity.  Advantages of FES braces include some evidence that there may be stimulation of the cortical neurons above the stimulation area, they are less cumbersome, and more discrete to wear.

A recent study looked at ..
Results 22-28 of 80