When: Friday, March 6, noon - 3 p.m.
Where: MS Center at Swedish
1600 East Jefferson Street, A Level
Seattle, WA 98122
RSVP: Mallory Higgins, 206-320-2200
Falls happen. Fall incidence can increase with disability. Falls in multiple sclerosis (MS) are common and often occur due to motor weakness, imbalance, gait impairment, and not using the adaptive equipment (cane, walker, orthotic) designed to help one ambulate more effectively and safely.
Falls can result in injury. This injury might only be an embarrassment to one’s pride; however, at other times, falls can contribute to more serious problems such as a fractured hip, a head injury, and in the worst case scenario, death. It is therefore important that we take a proactive approach to fall prevention.
The International Multiple Sclerosis Falls Prevention Research Network has examined the roles of various fall prevention rehabilitation programs to learn which might be the most effective in reducing fall risk and falls (click here to read the research). A critical element, in all programs, is that participant improvement in fall risk and fall reduction is primarily achieved in the short term but not sustained over the long term. The reality is that most people's motivation, to continue a program, dramatically "falls off" over time.
Here's a summary of the different types of program settings:
The MS Center at Swedish Neuroscience Institute played a major role in a research study that recently garnered national attention. This research was published in JAMA Neurology. This research investigated the effect of high dose immunosuppressive followed by hematopoietic stem cell therapy.
This therapy consists of collecting hematopoietic stem cells from patients' blood. Patients then undergo an intense course of immunosuppressive therapy with four medications. This therapy is sufficient to eliminate most of the patient’s bone marrow including white blood cells. The hematopoietic stem cells are then given back to the patient so that their bone marrow may be reconstituted. In multiple sclerosis (MS), the immune system attacks the brain. The hope is that with this therapy the reconstituted immune system will have less of a tendency to attack the brain and that the disease will stabilize.
This is our second study on this technique in MS. The first study investigated the effect of this treatment on patients with more advanced disease. All but ...
Traditionally, MS has been divided into four clinical courses: relapsing/remitting, primary progressive, secondary progressive and progressive relapsing. These four were intended as descriptions of the different courses that MS could take in patients, and were not based on any particular understanding of the biology of the disease, the cause of the disease, or even the prognosis of patients with the different types of MS. Over the years, our understanding of MS has improved, and these descriptions of the disease course no longer meet our needs to describe the disease.
Over the past couple of years, there has been a revision of our classification of MS, resulting in a publication in July 2014. The recommendations of this revision have been ..