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'MS' Swedish Multiple Sclerosis Blog posts

FDA approves 40 mg/mL Copaxone for 3 times a week

The U.S. Food and Drug Administration (FDA) has approved the three-times-a-week COPAXONE® 40mg/mL, a new dose of COPAXONE® on Jan 28, 2014.  This new formulation will allow for a less frequent dosing regimen administered by injection for patients with relapsing forms of multiple sclerosis (MS). In addition to the newly approved dose, daily COPAXONE® 20 mg/mL will continue to be available.

The FDA approval is based on data from ...

Weak link between epsilon toxin and MS

A recent article has been published suggesting that MS may be caused by a bacterial toxin. The bacteria is Clostridium Perfringens, a common bacteria found in soil and a cause of food poisoning. This bacteria can produce a number of toxins, one of which is the epsilon toxin.

This study found that about 10% of people with multiple sclerosis (MS) had antibodies to the epsilon toxin, compared to 1% of people without MS. In pathology specimens from mice, the epsilon toxin was found to bind to blood vessels in the retina of the eye, and to myelin in the brain. The authors also reported a single case of a woman with MS who was infected with Clostridium Perfringens and that was producing the epsilon toxin.

Though this study has been widely discussed online, I think that it is unlikely that this will be the answer to the MS problem. This study was primarily in pathology tissue, which found that the toxin was able to bind to myelin. Many more studies will be needed to determine whether this toxin is capable of causing damage to myelin of the type that is seen in MS. There are many other known toxins to myelin, but so far none seem to be the cause of MS.

They tried to show that ..

Swedish MS Center design recognized

Less than two years old, the Swedish Multiple Sclerosis Center has already received an overwhelming amount of praise from patients and physicians alike for its holistic approach to world class care.

Now we can add one more accolade to the list.

Healthcare Design magazine recently recognized the MS Center’s patient and family waiting area as a finalist in the Family Spaces category of its Healthcare Design Remodel Renovation Competition.The entire piece beautifully encapsulates the approach, design and ultimately the quality of care that the MS Center strives to deliver. Here is an excerpt of one of the judge’s comments:

“The entire design is a phenomenal reflection of a deep understanding of the unique needs of patients with multiple sclerosis. It is apparent the design team did their research, listened to the voice of the patient and caregivers, and integrated evidence-based design principles….”

That’s high praise, and it is rewarding to know that the attention we paid to every detail — from furniture and flooring to treatment and waiting areas — was noticed. But it is even more rewarding to know that the center has become an incredible resource in treating those diagnosed with MS, a degenerative disease that strikes the central nervous system.

Information on multiple sclerosis and flu

Now that flu season is upon us, we are getting a lot of questions about the relationship between MS and infections, including influenza. MS does not impair the ability to fight off infections. Likewise, most of the treatments for MS do not impair the ability to fight infections, though there are a few exceptions to this. Most people with MS will therefore not be at any higher risk of colds or flu than the general population. However, infections may affect the MS. People with MS have an increased risk of having an MS attack at the time of infections, including colds, flu, pneumonia, bladder infections, etc. Some have estimated that about 1 out of 10 infections will be accompanied by an MS attack. Likewise, for every MS attack about 1 in 10 will be preceded by an infection. This means that about 90% of MS attacks occur in the absence of an infection.
 
Another important question is the role of vaccination in MS. In general, vaccinations do not seem to cause MS attacks. Because the vaccinations do not usually cause MS attacks, but the flu can cause an MS attack about 1 in 10 times, most neurologists recommend that MS patients receive the influenza vaccine. It is ...

MS in the Pacific Northwest on 12/9

All are invited to attend the presentation, “Multiple Sclerosis in the Pacific Northwest,” on Monday, Dec. 9 at 7 p.m. in Kirkland. I'll discuss multiple sclerosis as a disease, trends, changes in its distribution around the world, and how it uniquely impacts our region. The presentation is free and is open to all ages. Click here for more information.

2013 World Atlas of MS published

The 2013 World Atlas of MS has been published by MS International Foundation and is available here. The key findings are:

  1. The estimated number of people with MS has increased from 2.1 million in 2008 to 2.3 million in 2013
  2. The 2:1 ratio of women to men with MS has not changed significantly since 2008
  3. Substantial global inequalities remain in terms of access to treatment and medical care

Constraint induced movement therapy in MS may be equally effective as in stroke

Constraint induced movement therapy (CIMT), formerly called “forced use” is a treatment for impaired function of an upper extremity. It has been established as an effective evidence-based form of treatment for rehab of impaired upper extremity (UE) function for post stroke hemiparesis. The core features of CIMT are massed practice (high repetitions) and to overcome learned non-use thru behavior modification. The typical training protocol involves a 2 week period of physical restraint of the less-involved side (90% of the waking hours) and intensive training (3 hours/day) focused on movement patterns of the involved hand and arm. The physical restraint is usually a padded mitt, sling or glove thereby restricting stronger arm use.
At a recent ECTRIMS/RIMS meeting, this form of therapy was presented as being equally effective in

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