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Neuroscience (SNI) Blog

'neuroscience' Neuroscience (SNI) posts

Deciding to have Deep Brain Stimulation (DBS) for PD, ET, or dystonia

Choosing to undergo elective deep brain stimulation (DBS) surgery is a big deal.

I have walked through the process with hundreds of patients over the past 10 years and see many struggle with the choice to undergo brain surgery, as they seek to improve their quality of life. Many people have adapted to compensate for the movement disorder with creativity and determination.

In spite of this, after the best medical options have been exhausted, DBS is increasingly offered as a viable treatment option.

Keys to making the best decision for you are:

SNI Research Aims to Expand Cerebral Palsy Therapy Options

Before they learn to crawl or walk, about 10,000 babies every year in the United States will develop a condition that will change how they will do just that. Cerebral palsy (CP) is a neurological condition caused by a brain injury before birth, during delivery or before a child’s second birthday. An estimated 800,000 Americans live with CP.

The most common symptom in CP is spasticity, an increase in muscle tension that impairs proper movement. Abnormal postures or movements, weakness or loss of muscle control and rigidity are also part of the constellation of CP signs and symptoms. While physical therapy remains the cornerstone for treatment, new medications and therapies for CP are being developed to help improve and manage symptoms.

Currently, Swedish Neuroscience Institute is participating in a study to determine the safety and tolerability of one such medication. Dalfampridine (AMPYRA ®) is a medication currently used to help improve walking speed in multiple sclerosis (MS) patients. This phase I clinical trial aims to evaluate AMPYRA’s® safety, tolerability and its effect on sensorimotor function of adults with CP. The study will look at how single and multiple doses of the medication have on CP patients, including:

  • Hand strength
  • Manual dexterity
  • Walking speed
  • Gait

There is no cure for cerebral palsy. Therapies for CP ...

Announcing New Swedish Cerebrovascular Support Group

It is with great pleasure that I announce the beginning of the Swedish Cerebrovascular Support Group. Over the last several months, the care team here at Swedish has had many patients reach out and ask if a service like this was available. I am so glad that the answer is now yes!

Receiving a diagnosis like a cerebral aneurysm is for many a scary and stressful situation. Support groups are a fantastic way for people to alleviate fear and anxiety through discussion and education. These meetings will be a place to connect patients, family members, and caregivers together to share their experiences and advise with one another. The group is open to patients and family members of patients that have been diagnosed with or treated for a cerebral aneurysm or arteriovenous malformation (AVM).

Using Ultrasound for Treatment of Brain Hemorrhage

In September, I co-authored this cover article in the Journal of Neurosurgery on the results of a study using ultrasound for the treatment of brain hemorrhage. The study involved 33 patients with spontaneous intracerebral hemorrhage who were screened for inclusion in a SNI clinical study known as “SLEUTH” (Safety of Lysis with Ultrasound in the Treatment of Intracerebral and Intraventricular Hemorrhage). You can the abstract and full text of the article or see background information on the study, and watch a related video on WebMD.

SNI award from NIH - 2.2M

Swedish Neuroscience Institute was awarded a 7-year, $2.2M grant by the National Institute of Neurological Disease and Stroke (NINDS) to participate in the NeuroNEXT program, a national consortium of 25 neuroscience centers of excellence that will conduct early-stage clinical trials. John W. Henson, MD, FAAN, and Daniel S. Rizzuto, PhD, will lead the effort at Swedish. Swedish Neuroscience Institute was the only non-university hospital chosen to participate, highlighting the value of Swedish’s investments in research and clinical infrastructure. For more information about NeuroNEXT click here

David Newell, M.D., co-authors cover article in Journal of Neurosurgery

David Newell, M.D., neurosurgeon and co-executive director of the Swedish Neuroscience Institute (SNI), co-authored the cover article in the September Journal of Neurosurgery on the results of a study using ultrasound for the treatment of brain hemorrhage. The study involved 33 patients with spontaneous intracerebral hemorrhage who were screened for inclusion in a SNI clinical study known as “SLEUTH” (Safety of Lysis with Ultrasound in the Treatment of Intracerebral and Intraventricular Hemorrhage). Read the abstract and full text of the article. Read background information on the study. Watch a related video on WebMD.

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