Research and progress for progressive Multiple Sclerosis (MS)

Research and progress for progressive Multiple Sclerosis (MS)

By Angeli Mayadev, MD
Physical Medicine & Rehabilitation, Swedish Multiple Sclerosis Center

I am delighted to write the blog over the Progressive MS session that was given at ECTRIMS 2013.  Much emphasis has been given to the need for more research in the fields of progressive MS.  The majority of MS patients fit into this broad category: primary progressive MS, secondary progressive MS, and progressive relapsing forms of the disease.  During a session devoted to progressive MS, leaders in the field discussed several initiatives underway to address the challenges presented by these forms of the disease. 

Rehabilitation is a mainstay and key to improving the lives of patients with progressive MS. Many patients describe their progression in terms of mobility decline, which is a major target of improvement in rehabilitation programs.

The first session was devoted to confusion surrounding the definition of “progression in MS.”  We use MRI and physical examination changes as well as patient symptoms as a means to define progression.  In the field of MS rehab, we use various physical test and scales as “rehab biomarkers” of progression (examples are the 6 min walk test, 25 ft timed walk, and the berg balance scale). There is still no specific defining terms of what constitutes progression of the disease.

There are various medication trials underway aimed at the progressive population.  Many of these drugs are in trial for relapsing remitting MS (RRMS) and/or are already approved for RRMS and may hold promise for progressive MS. The Progressive MS Alliance is a newly formed international effort to connect resources and experts around the world to find the answers and develop the solutions to end progressive MS.  There is a call for research abstracts that will be supported through this alliance.  According to the MS Society, 85 separate presentations at ECTRIMS specifically referenced progressive MS.  This shows how the MS community is trying to fill a need for treatment and research in this area of MS.

Comments
Karin Bosela
It is about time someone looked into treatments for PPMS and the other progressive forms of this disease as they generally focus on the remitting relapsing patients. However, I have to wonder if the drug companies have an another motive - like we are missing a portion of profits from the MS population. I an extremely suspect when research is done my doctors and scientist owned by Big Pharma as they have failed in every aspect to cure any disease without causing additional ones for centuries now. What better way to assure your customer base. Research needs to be focused on stem cell therapy not drugs. Let the cells that GOD created in your body heal your body with a little re-direction. It is sad that no one actually wants to cure this degenerative disease just put profit before patients.
12/25/2013 4:10:53 AM
Leave comment



 Security code