Each optic nerve contains approximately one million nerve cells (neurons) that connect the eye to the brain. Inflammation from multiple sclerosis (MS) can affect the optic nerves. Therefore, it is very common for people with MS to have vision problems.
When MS inflammation affects optic nerve neurons, they may lose their protective myelin coating, a process called demyelination. This caused signals through the neurons to slow down, resulting in blurred vision.
Medications may repair myelin, but studies are limited.
4-aminopyridine (4-AP) is a medicine used to treat symptoms of MS caused by demyelination. It stabilizes movement of potassium ions through the surface of demyelinated neurons, making it easier for them to conduct signals.
Historically, 4-AP has only been available through compounding pharmacies, so studies of its use have been ...